IL-12A p35/p70 Antibody (B-T21) is a mouse monoclonal IgG1 antibody that detects Interleukin-12A p35 in human samples through flow cytometry (FCM). IL-12A p35 is a crucial subunit of the heterodimeric cytokine IL-12, which plays a significant role in the immune response by promoting the differentiation of T helper cells and enhancing the production of interferon-γ (IFN-γ) from T cells and natural killer (NK) cells. This cytokine is secreted by various antigen-presenting cells, including phagocytes and B cells, and is vital for mediating antiviral immunity. IL-12A p35 initiates and regulates immune responses, particularly during viral infections such as those caused by Epstein-Barr virus (EBV) and cytomegalovirus (CMV). IL-12A p35 functions as the biologically active component responsible for signal transduction through the IL-12 receptor, making IL-12A p35 essential for effective immune signaling. Anti-IL-12A p35/p70 antibody (B-T21) serves as an invaluable tool for researchers studying immune responses and cytokine signaling pathways, providing insights into the mechanisms of immune regulation and potential therapeutic targets in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-12A p35/p70 Antibody (B-T21) | sc-65323 | 100 µg/ml | $322.00 |