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IgG2a Antibody (RMG2a-62) is a rat monoclonal IgG2a antibody that detects IgG2a in mouse samples through flow cytometry (FCM). IgG2a is a subclass of immunoglobulin G that plays a crucial role in the immune response, particularly in its ability to activate complement pathways and mediate antibody-dependent cellular cytotoxicity. This subclass is known for its high affinity for Fc receptors on immune cells, which enhances effectiveness in targeting pathogens. The unique structure of IgG2a, characterized by two heavy chains and two light chains, allows for the formation of a flexible hinge region that facilitates binding to antigens and immune effector cells. This structural feature enables IgG2a to effectively engage with various immune components, thereby amplifying the immune response against infections. The ability of IgG2a to cross the placenta provides passive immunity to the developing fetus, ensuring protection during early stages of life when the fetal immune system is not fully developed. IgG2a Antibody (RMG2a-62) serves as an essential tool for researchers studying immune responses in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IgG2a Antibody (RMG2a-62) | sc-53758 | 100 µg/ml | $316.00 |