IgG light chain Antibody (IVA285-1): sc-51643

IgG light chain Antibody (IVA285-1) is a mouse monoclonal IgG light chain antibody that detects IgG light chain protein of bovine origin by western blotting (WB), immunofluorescence (IF), and flow cytometry (FCM). Anti-IgG light chain antibody (IVA285-1) is available as a non-conjugated format, providing researchers with a reliable tool for studying immunoglobulin structure and function. IgG light chain plays a crucial role in immune response, as IgG light chain is essential for forming functional antibodies that bind to antigens and facilitate their neutralization or destruction. Each IgG molecule consists of two light chains and two heavy chains, linked by disulfide bonds, forming a Y-shaped structure vital for antigen-binding capabilities. Light chains are classified into kappa (κ) and lambda (λ) types, with specific type produced during B-cell development. Understanding IgG light chain expression dynamics and interactions with heavy chains helps elucidate mechanisms of antibody diversity and specificity, fundamental to effective immune responses.

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IgG light chain Antibody (IVA285-1) References:

1. Comparison of various implicit solvent models in molecular dynamics simulations of immunoglobulin G light chain dimer.  |  Król, M. 2003. J Comput Chem. 24: 531-46. PMID: 12632469
2. Analysis of the effect of electrostatic energy truncation in molecular dynamics simulations of immunoglobulin G light chain dimer.  |  Król, M. 2003. J Mol Model. 9: 316-24. PMID: 12898291
3. Analysis of correlated domain motions in IgG light chain reveals possible mechanisms of immunological signal transduction.  |  Król, M., et al. 2005. Proteins. 59: 545-54. PMID: 15778960
4. [Bullous poikilodermatitic amyloidosis of the skin with junctional bulla development in IgG light chain plasmacytoma of the lambda type. Histology, immunohistology and electron microscopy].  |  Winzer, M., et al. 1992. Hautarzt. 43: 199-204. PMID: 1597368
5. A case of monoclonal immunoglobulin light- and heavy-chain deposition disease exhibiting atypical deposition with fibrillary structures, successfully treated with chemotherapy.  |  Nakatsuka, A., et al. 2005. Clin Nephrol. 64: 221-7. PMID: 16175947
6. Prion urine comprises a glycosaminoglycan-light chain IgG complex that can be stained by Congo red.  |  Halimi, M., et al. 2006. J Virol Methods. 133: 205-10. PMID: 16386805
7. Effects of paraprotein heavy and light chain types and free light chain load on survival in myeloma: an analysis of patients receiving conventional-dose chemotherapy in Medical Research Council UK multiple myeloma trials.  |  Drayson, M., et al. 2006. Blood. 108: 2013-9. PMID: 16728700
8. Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors.  |  Giritch, A., et al. 2006. Proc Natl Acad Sci U S A. 103: 14701-6. PMID: 16973752
9. A partial sequence of an IgG light chain using continuous flow HPLC-FAB mass spectroscopy.  |  Claydon, MA., et al. 1995. Biochem Soc Trans. 23: 633S. PMID: 8654818

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-IgG light chain Antibody (IVA285-1) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-IgG light chain Antibody (IVA285-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

IgG light chain Antibody (IVA285-1) Specifications

Alternate Product Name: IgG light chain

Product Clone Name: IVA285-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG

Amino Acids:

Epitope Target: IgG

Epitope Species: bovine

Product Reactivity/Detection: IgG light chain

Species Reactivity/Detection: bovine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF, FCM

Vialing Information: Each vial contains 100 µg IgG in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for IgG light chain Antibody (IVA285-1): N/A