IGFN1 Antibody (S-2): sc-81855

IGFN1 Antibody (S-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects IGFN1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-IGFN1 antibody (S-2) is available as a non-conjugated monoclonal isotype antibody. IGFN1, also known as immunoglobulin-like and fibronectin type III domain containing 1, consists of 868 amino acids and plays a crucial role in cellular processes, particularly in muscle development and maintenance. IGFN1 is primarily located in the cytoplasm and is believed to be involved in the regulation of cell signaling pathways that are essential for muscle fiber integrity and function. Proper localization of IGFN1 is vital, as disruptions in expression or localization can lead to muscle-related disorders and contribute to disease pathogenesis. IGFN1 has been implicated in the modulation of cellular responses to stress, highlighting its importance in maintaining cellular homeostasis. With diverse applications in research, IGFN1 monoclonal antibody (S-2) serves as a valuable tool for studying IGFN1′s role in health and disease.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

IGFN1 Antibody (S-2) References:

1. Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.  |  Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
2. New insights into the evolution of chromosome 1.  |  Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
3. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.  |  McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
4. Cell biology: ageing nucleus gets out of shape.  |  Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
5. Chromosome 1 abnormalities in multiple myeloma.  |  Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
6. Lamin A-dependent nuclear defects in human aging.  |  Scaffidi, P. and Misteli, T. 2006. Science. 312: 1059-63. PMID: 16645051
7. Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.  |  Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
8. The DNA sequence and biological annotation of human chromosome 1.  |  Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
9. Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1.  |  Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-IGFN1 Antibody (S-2) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-IGFN1 Antibody (S-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

IGFN1 Antibody (S-2) Specifications

Alternate Product Name: IGFN1

Product Clone Name: S-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 720-819

Epitope Target: IGFN1

Epitope Species: human

Product Reactivity/Detection: IGFN1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for IGFN1 Antibody (S-2): N/A