Molecular structure of IGEPAL CA-630, CAS Number: 9002-93-1
IGEPAL CA-630 (CAS 9002-93-1)
See product citations (3)
Alternate Names:
Octylphenyl-polyethylene glycol
Application:
IGEPAL CA-630 is a non-ionic, non-denaturing detergent for in situ denaturation
CAS Number:
9002-93-1
Molecular Formula:
(C2H4O)nC14H22O, n=9 or 10
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
IGEPAL CA-630 is a nonionic, octylphenol ethoxylate surfactant used in biochemistry and molecular biology research. It serves as a detergent to solubilize proteins by disrupting lipid-lipid and lipid-protein interactions, thereby helping to isolate membrane proteins and lipids from cells. IGEPAL CA-630 is also employed as a lysing agent for the disruption of cell membranes to release cytoplasmic contents during cell lysis procedures. In addition, it is utilized in the preparation of nuclear extracts and in immunoassays as a blocking agent to reduce nonspecific binding. In studies involving protein-protein interactions, IGEPAL CA-630 is used to maintain proteins in solution, facilitating the study of their function and structure. Its utility in a broad range of applications makes it a staple in laboratories focusing on cellular and molecular analysis.
IGEPAL CA-630 (CAS 9002-93-1) References
- Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes. | Lencesova, L., et al. 2004. J Biol Chem. 279: 2885-93. PMID: 14593108
- Controlled release of the fibronectin central cell binding domain from polymeric microspheres. | Bouissou, C., et al. 2004. J Control Release. 95: 557-66. PMID: 15023466
- The physicochemical parameters of marker compounds and vehicles for use in in vitro percutaneous absorption studies. | Kaca, M., et al. 2008. Altern Lab Anim. 36: 189-200. PMID: 18522485
- Mitigation of calcification and cytotoxicity of a glutaraldehyde-preserved bovine pericardial matrix: improved biocompatibility after extended implantation in the subcutaneous rat model. | Neethling, WM., et al. 2010. J Heart Valve Dis. 19: 778-85. PMID: 21214104
- Alteration in cell surface properties of Burkholderia spp. during surfactant-aided biodegradation of petroleum hydrocarbons. | Mohanty, S. and Mukherji, S. 2012. Appl Microbiol Biotechnol. 94: 193-204. PMID: 22089390
- Discrimination of infectious hepatitis A virus and rotavirus by combining dyes and surfactants with RT-qPCR. | Coudray-Meunier, C., et al. 2013. BMC Microbiol. 13: 216. PMID: 24083486
- Purification and reconstitution of human membrane-bound DHRS7 (SDR34C1) from Sf9 cells. | Skarka, A., et al. 2014. Protein Expr Purif. 95: 44-9. PMID: 24316191
- An optimised direct lysis method for gene expression studies on low cell numbers. | Le, AV., et al. 2015. Sci Rep. 5: 12859. PMID: 26242641
- High-efficiency extracellular release of free fatty acids from Aspergillus oryzae using non-ionic surfactants. | Tamano, K., et al. 2017. J Biotechnol. 248: 9-14. PMID: 28300661
- An in-well direct lysis method for rapid detection of SARS-CoV-2 by real time RT-PCR in eSwab specimens. | Jørgensen, RL., et al. 2021. J Virol Methods. 289: 114062. PMID: 33428990
- Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application. | Lu, S., et al. 2022. PLoS One. 17: e0268340. PMID: 35544541
- Strategic optimization of conditions for the solubilization of GST-tagged amphipathic helix-containing ciliary proteins overexpressed as inclusion bodies in E. coli. | Shendge, AA. and D'Souza, JS. 2022. Microb Cell Fact. 21: 258. PMID: 36510188
- Evidence for a tubulin-containing lipid-protein structural complex in ciliary membranes. | Stephens, RE. 1985. J Cell Biol. 100: 1082-90. PMID: 3980579
- Standardization of an enzyme-linked immunosorbent assay for the determination of protein tyrosine kinase activity. | Schraag, B., et al. 1993. Anal Biochem. 211: 233-9. PMID: 7686354
- The specific subcellular localization of two isoforms of cytochrome b5 suggests novel targeting pathways. | D'Arrigo, A., et al. 1993. J Biol Chem. 268: 2802-8. PMID: 8428954
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IGEPAL CA-630, 25 ml | sc-280818 | 25 ml | $40.00 | |||
IGEPAL CA-630, 250 ml | sc-280818A | 250 ml | $62.00 |