IFN-γ/Interferon gamma Antibody (F3): sc-59993
- IFN-γ/Interferon gamma Antibody (F3) is a rat monoclonal IgG2a, cited in 6 publications, provided at 100 µg/ml
- raised against IFN-γ of mouse origin
- recommended for detection of IFN-γ of mouse origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (F3). This work is in progress.
IFN-γ Antibody (F3) is a rat monoclonal IgG2a antibody that detects interferon (IFN)-γ in mouse samples through western blotting (WB) and immunoprecipitation (IP) applications. IFN-γ plays a crucial role in the immune response, acting as a potent antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. IFN-γ modulates T cell growth and differentiation while inhibiting B cell proliferation, thereby shaping the adaptive immune response. The active form of IFN-γ is a homodimer, with each subunit comprising six helices, and this dimeric structure is stabilized by non-covalent interactions at the interface of the helices. The precursor of IFN-γ consists of 166 amino acids, which includes a 23 amino acid secretory sequence, and functionality is further enhanced by variable glycosylation, leading to multiple forms that can exist as dimers and tetramers under non-denaturing conditions. Anti-IFN-γ antibody (F3) is an essential tool for researchers studying immune responses and the intricate mechanisms of cytokine signaling in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (F3) | sc-59993 | 100 µg/ml | $322.00 |