IFN-β Antibody (7F-D3): sc-57201
- IFN-β Antibody (7F-D3) is a rat monoclonal IgG1, cited in 27 publications, provided at 100 µg/ml
- raised against IFN-β of mouse origin
- recommended for detection of IFN-β of mouse origin by WB, IP and ELISA; non cross-reactive with IFN-α or IFN-γ
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-β Antibody (7F-D3). This work is in progress.
IFN-β Antibody (7F-D3) is a rat monoclonal IgG1 antibody that detects IFN-β of mouse origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-IFN-β antibody (7F-D3) is raised against IFN-β of mouse origin. IFN-β (7F-D3) antibody is available in a non-conjugated form, providing researchers with a versatile tool for studying this critical cytokine. IFN-β, a member of the type I interferon family, plays a vital role in the immune response, particularly in the defense against viral infections. IFN-β is primarily produced by fibroblasts and epithelial cells in response to viral stimuli, and IFN-β secretion leads to the activation of various immune cells, enhancing their antiviral activities. IFN-β′s importance extends beyond antiviral properties; IFN-β also exhibits antitumor and immunomodulatory effects, making IFN-β a key player in therapeutic strategies for malignancies, myelodysplastic syndromes, and autoimmune diseases. The gene encoding IFN-β is located on human chromosome 9, clustered with other type I interferon genes, which underscores IFN-β′s evolutionary significance in the immune system. Using IFN-β (7F-D3) monoclonal antibody, researchers can gain deeper insights into the functional dynamics of this cytokine and its interactions within the immune landscape, ultimately contributing to the development of novel therapeutic approaches.
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IFN-β Antibody (7F-D3) References:
- IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29. | Sirén, J., et al. 2005. J Immunol. 174: 1932-7. PMID: 15699120
- The production of IL-1 receptor antagonist in IFN-beta-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1. | Molnarfi, N., et al. 2005. J Immunol. 174: 2974-80. PMID: 15728510
- TRAIL is a key target in S-phase slowing-dependent apoptosis induced by interferon-beta in cervical carcinoma cells. | Vannucchi, S., et al. 2005. Oncogene. 24: 2536-46. PMID: 15735750
- Antigenic structure of human interferon omega 1 (interferon alpha II1): comparison with other human interferons. | Adolf, GR. 1987. J Gen Virol. 68 (Pt 6): 1669-76. PMID: 2438379
- Intrinsic ligand binding properties of the human and bovine alpha-interferon receptors. | Lim, JK., et al. 1994. FEBS Lett. 350: 281-6. PMID: 8070579
- An anti-cytokine bioactivity assay for interferons-alpha, -beta and -omega. | Mire-Sluis, AR., et al. 1996. J Immunol Methods. 195: 55-61. PMID: 8814320
- Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population. | Hussain, M., et al. 1996. J Interferon Cytokine Res. 16: 853-9. PMID: 8910771
- Contributions of cloned type I interferon receptor subunits to differential ligand binding. | Cutrone, EC. and Langer, JA. 1997. FEBS Lett. 404: 197-202. PMID: 9119063
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-β Antibody (7F-D3) | sc-57201 | 100 µg/ml | $316.00 |