Date published: 2025-11-21

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IFI-16 Antibody (H-8): sc-136976

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Datasheets
  • IFI-16 Antibody (H-8) is a mouse monoclonal IgM κ provided at 200 µg/ml
  • raised against amino acids 731-785 mapping at the C-terminus of IFI-16 of human origin
  • recommended for detection of IFI-16 of human origin by WB, IP, IF, IHC(P) and ELISA
  • See IFI-16 (1G7): sc-8023 for IFI-16 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFI-16 Antibody (H-8). This work is in progress.

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    IFI-16 Antibody (H-8) is a mouse monoclonal IgM antibody that detects IFI-16 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). IFI-16 is a crucial protein primarily located in the nucleus, where IFI-16 plays a significant role in the immune response by acting as a sensor for viral DNA, thereby triggering the production of type I interferons and other cytokines. This function is vital for the innate immune system, as IFI-16 helps to initiate a rapid defense against viral infections. Additionally, IFI-16 has been implicated in the regulation of cell proliferation and apoptosis, making IFI-16 an important player in both immune regulation and potential tumorigenesis. Anti-IFI-16 antibody (H-8) specifically targets IFI-16, allowing researchers to explore diverse roles in cellular processes and interactions with other proteins, such as those involved in the signaling pathways that modulate immune responses. With robust reactivity and versatility in various applications, IFI-16 monoclonal antibody (H-8) serves as an essential tool for researchers studying immune mechanisms and related diseases.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    IFI-16 Antibody (H-8)

    sc-136976
    200 µg/ml
    $316.00

    Can IFI-16 (H-8): sc-136976 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: jerojero
    Thank you for your question. Yes, IFI-16 (H-8): sc-136976 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Great immunoperoxidase nuclear staining inGreat immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human urinary bladder tissue. -SCBT QC
    Date published: 2015-05-20
    Rated 5 out of 5 by from Satisfactory Western Blot data of IFISatisfactory Western Blot data of IFI-16 expression in non-transfected 293, human IFI-16 transfected 293 and HuT 78 whole cell lysates. -SCBT QC
    Date published: 2013-01-25
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    IFI-16 Antibody (H-8) is rated 5.0 out of 5 by 2.
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