Date published: 2025-11-21

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IFI-16 Antibody (G-4): sc-166472

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Datasheets
  • IFI-16 Antibody (G-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 712-729 at the C-terminus of IFI-16 of human origin
  • recommended for detection of IFI-16 of human origin by WB, IP, IF, IHC(P) and ELISA
  • See IFI-16 (1G7): sc-8023 for IFI-16 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IFI-16 Antibody (G-4) for WB and IHC(P) applications. These reagents are now offered in bundles with IFI-16 Antibody (G-4) (see ordering information below).

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    IFI-16 Antibody (G-4) is a mouse monoclonal IgG1 antibody that detects IFI-16 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). IFI-16 plays a significant role in immune response, particularly in viral DNA recognition, which is essential for initiating appropriate immune reactions. IFI-16 is primarily localized in the nucleus, functioning as a transcriptional regulator and modulating gene expression in response to viral infections. Nuclear localization of IFI-16 enables direct interaction with DNA and other nuclear factors, influencing transcriptional activity of genes critical for immune response. IFI-16 forms complexes with other proteins, such as myeloid cell nuclear differentiation antigen (MNDA), enhancing immune signaling pathways. IFI-16′s ability to be induced by interferon-gamma in various cell types underscores its importance in adaptive immune response, making anti-IFI-16 antibody (G-4) an invaluable tool for studying immune mechanisms and viral pathogenesis.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    IFI-16 Antibody (G-4)

    sc-166472
    200 µg/ml
    $316.00

    IFI-16 Antibody (G-4): m-IgG Fc BP-HRP Bundle

    sc-540107
    200 µg Ab; 10 µg BP
    $354.00

    IFI-16 Antibody (G-4): m-IgG1 BP-HRP Bundle

    sc-541907
    200 µg Ab; 20 µg BP
    $354.00

    IFI-16 (G-4) Neutralizing Peptide

    sc-166472 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-166472 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from very good for IFnice (mostly nuclear) IF staining in BJ and IMR90 fibroblasts (1:100 dilution).
    Date published: 2017-01-25
    Rated 5 out of 5 by from Strong band in WB in human transfected 293Strong band in WB in human transfected 293 whole cell lysates. -SCBT QC
    Date published: 2015-06-16
    Rated 5 out of 5 by from Robust signal in WB in Jurkat nuclear extractRobust signal in WB in Jurkat nuclear extract. -SCBT QC
    Date published: 2015-04-08
    Rated 5 out of 5 by from Produced great immunoperoxidase nuclear stainingProduced great immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human urinary bladder. -SCBT QC
    Date published: 2015-02-03
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    IFI-16 Antibody (G-4) is rated 5.0 out of 5 by 4.
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