IEM 1754 dihydrobromide (CAS 162831-31-4)
Alternate Names:
N-(Tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1,5-pentanediamine dihydrobromide
Application:
IEM 1754 dihydrobromide is a blocker of AMPA receptors that is voltage-dependent and open-channel
CAS Number:
162831-31-4
Molecular Weight:
412.25
Molecular Formula:
C16H30N2•2HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
IEM-1754 dihydrobromide is a compound that effectively blocks AMPA receptors, which are voltage-dependent open channels. Its mechanism of action involves selectively targeting GluR2 subunit-lacking receptors, which are known to be permeable to calcium ions (Ca2+). This selective blocking property of IEM-1754 dihydrobromide makes it particularly effective in modulating the activity of AMPA receptors that lack the GluR2 subunit. By doing so, it can influence the flow of calcium ions through these receptors, leading to significant impact on cellular processes and signaling pathways.
IEM 1754 dihydrobromide (CAS 162831-31-4) References
- GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer. | Vijay, GV., et al. 2019. Breast Cancer Res. 21: 37. PMID: 30845991
Inhibitor of:
PARP-10.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IEM 1754 dihydrobromide, 10 mg | sc-362747 | 10 mg | $172.00 | |||
IEM 1754 dihydrobromide, 50 mg | sc-362747A | 50 mg | $729.00 |