Date published: 2026-5-12

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Idarubicin (CAS 58957-92-9)

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Datasheets
Alternate Names:
4-Demethoxydaunorubicin
CAS Number:
58957-92-9
Molecular Weight:
497.49
Molecular Formula:
C26H27NO9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Idarubicin (CAS 58957-92-9) References

  1. High-dose cytarabine (24 g/m2) in combination with idarubicin (HiDAC-3) results in high first-cycle response with limited gastrointestinal toxicity in adult acute myeloid leukaemia.  |  Low, M., et al. 2013. Intern Med J. 43: 294-7. PMID: 22757980
  2. Idarubicin-loaded beads for chemoembolisation of hepatocellular carcinoma: results of the IDASPHERE phase I trial.  |  Boulin, M., et al. 2014. Aliment Pharmacol Ther. 39: 1301-13. PMID: 24738629
  3. Idarubicin-loaded methoxy poly(ethylene glycol)-b-poly(l-lactide-co-glycolide) nanoparticles for enhancing cellular uptake and promoting antileukemia activity.  |  Liang, B., et al. 2019. Int J Nanomedicine. 14: 543-556. PMID: 30666113
  4. Idarubicin Stimulates Cell Cycle- and TET2-Dependent Oxidation of DNA 5-Methylcytosine in Cancer Cells.  |  Zhong, S., et al. 2019. Chem Res Toxicol. 32: 861-868. PMID: 30816036
  5. Equipotent doses of daunorubicin and idarubicin for AML: a meta-analysis of clinical trials versus in vitro estimation.  |  Adige, S., et al. 2019. Cancer Chemother Pharmacol. 83: 1105-1112. PMID: 30968179
  6. Idarubicin-loaded Beads for Chemoembolization of Hepatocellular Carcinoma: The IDASPHERE II Single-Arm Phase II Trial.  |  Guiu, B., et al. 2019. Radiology. 291: 801-808. PMID: 31038408
  7. Insights into idarubicin antimicrobial activity against methicillin-resistant Staphylococcus aureus.  |  She, P., et al. 2020. Virulence. 11: 636-651. PMID: 32423280
  8. Idarubicin, an Anthracycline, Induces Oxidative DNA Damage in the Presence of Copper (II).  |  Mizutani, H., et al. 2020. Anticancer Res. 40: 5399-5404. PMID: 32988859
  9. Optimization of idarubicin and cytarabine induction regimen with homoharringtonine for newly diagnosed acute myeloid leukemia patients based on the peripheral blast clearance rate: A single-arm, phase 2 trial (RJ-AML 2014).  |  Zhang, Y., et al. 2022. Am J Hematol. 97: 43-51. PMID: 34687467
  10. Idarubicin-induced oxidative stress and apoptosis in cardiomyocytes: An in vitro molecular approach.  |  Zhang, Y., et al. 2021. Hum Exp Toxicol. 40: S553-S562. PMID: 34787021

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Idarubicin, 10 mg

sc-507346
10 mg
$180.00