ICAM-1/CD54 Antibody (LB-2): sc-18908
- ICAM-1/CD54 Antibody (LB-2) is a mouse monoclonal IgG2b κ, cited in 14 publications, provided at 200 µg/ml
- raised against an intracellular epitope of ICAM-1 of human origin
- recommended for detection of ICAM-1 of human origin by WB, IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for functional studies, sc-18908 L, 200 µg/0.1 ml
- See ICAM-1/CD54 (G-5): sc-8439 for ICAM-1/CD54 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ICAM-1/CD54 Antibody (LB-2) for WB applications. These reagents are now offered in bundles with ICAM-1/CD54 Antibody (LB-2) (see ordering information below).
QUICK LINKS
ICAM-1 Antibody (LB-2) is a mouse monoclonal IgG2b kappa light chain antibody raised against an intracellular epitope of human ICAM-1, demonstrating reactivity with human species. Anti-ICAM-1 antibody (LB-2) is suitable for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). ICAM-1, also known as CD54 or intercellular adhesion molecule-1, is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. ICAM-1 plays a crucial role in mediating cell-cell adhesion by interacting with leukocyte integrins like LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18), facilitating leukocyte adhesion and transmigration across the endothelium during immune responses. ICAM-1′s function is vital for immune surveillance, inflammation, and signal transduction, making ICAM-1 significant in studies of immune and inflammatory diseases. Overexpression or aberrant regulation of ICAM-1 is associated with various pathological conditions, including autoimmune disorders, cardiovascular diseases, and cancer metastasis. Understanding ICAM-1′s role can aid in developing therapeutic strategies to modulate immune responses and treat inflammatory conditions. Anti-ICAM-1 antibody (LB-2) provides a valuable tool for researchers investigating the function and regulation of ICAM-1 in physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ICAM-1/CD54 Antibody (LB-2) | sc-18908 | 200 µg/ml | $316.00 | |||
ICAM-1/CD54 Antibody (LB-2): m-IgGκ BP-HRP Bundle | sc-533771 | 200 µg Ab; 40 µg BP | $354.00 | |||
ICAM-1/CD54 Antibody (LB-2): m-IgG2b BP-HRP Bundle | sc-549238 | 200 µg Ab; 10 µg BP | $354.00 | |||
ICAM-1/CD54 Antibody (LB-2) FITC | sc-18908 FITC | 200 µg/ml | $330.00 | |||
ICAM-1/CD54 Antibody (LB-2) L | sc-18908 L | 200 µg/0.1 ml | $316.00 | |||
ICAM-1/CD54 Antibody (LB-2) PE | sc-18908 PE | 200 µg/ml | $343.00 |