Ibutilide Fumarate (CAS 122647-32-9)
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Ibutilide fumarate is a class III antiarrhythmic agent that functions as a selective blocker of the rapid component of the delayed rectifier potassium current in cardiac cells. It exerts its mechanism of action by prolonging the action potential duration and refractory period in atrial and ventricular myocardial cells, leading to the inhibition of potassium channels. This results in the prolongation of the effective refractory period in atrial and ventricular muscle and the reduction of the action potential duration. Ibutilide fumarate′s mechanism of action involves the activation of slow inward sodium current, which leads to the depolarization of the membrane potential and the initiation of action potentials. It may increase intracellular calcium levels, which may contribute to its antiarrhythmic effects. Ibutilide fumarate′s mechanism of action involves the modulation of ion channels and intracellular calcium levels in cardiac cells, leading to alterations in action potential duration and refractory period.
Ibutilide Fumarate (CAS 122647-32-9) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ibutilide Fumarate, 10 mg | sc-211627 | 10 mg | $250.00 |