Ibuproxam (CAS 53648-05-8)
Alternate Names:
2-(4-Isobutylphenyl)-propiohydroxamic acid
CAS Number:
53648-05-8
Molecular Weight:
221.3
Molecular Formula:
C13H19NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ibuproxam is used to relieve pain and reduce inflammation. It works by inhibiting the production of prostaglandins, which are chemicals that cause pain and inflammation. Ibuproxam is a derivative of ibuprofen and has similar pharmacological properties. It is a white crystalline powder that is sparingly soluble in water. Ibuproxam is used to study the mechanisms of inflammation and pain. Its chemical structure and mode of action are utilized for understanding the biochemistry of inflammation and pain. Ibuproxam is used as a reference standard in analytical chemistry to test the purity of other NSAIDs.
Ibuproxam (CAS 53648-05-8) References
- Effects of the host cavity size and the preparation method on the physicochemical properties of ibuproxam-cyclodextrin systems. | Mura, P., et al. 1999. Drug Dev Ind Pharm. 25: 279-87. PMID: 10071820
- Comparative study of ibuproxam complexation with amorphous beta-cyclodextrin derivatives in solution and in the solid state. | Mura, P., et al. 2002. Eur J Pharm Biopharm. 54: 181-91. PMID: 12191690
- Thin layer chromatographic resolution of some 2-arylpropionic acid enantiomers using L-(-)-serine, L-(-)-threonine and a mixture of L-(-)-serine and L-(-)-threonine-impregnated silica gel as stationary phases. | Aboul-Enein, HY., et al. 2003. Biomed Chromatogr. 17: 325-34. PMID: 12884398
- Enantiomeric resolution of some 2-arylpropionic acids using L-(-)-serine-impregnated silica as stationary phase by thin layer chromatography. | Aboul-Enein, HY., et al. 2003. J Pharm Biomed Anal. 32: 1055-9. PMID: 12899993
- Contact and photocontact allergy to ketoprofen: clinical and experimental study. | Mozzanica, N. and Pigatto, PD. 1990. Contact Dermatitis. 23: 336-40. PMID: 2151373
- Wetting Kinetics: an Alternative Approach Towards Understanding the Enhanced Dissolution Rate for Amorphous Solid Dispersion of a Poorly Soluble Drug. | Verma, S. and Rudraraju, VS. 2015. AAPS PharmSciTech. 16: 1079-90. PMID: 25672820
- Mangosteen pericarp extract embedded in electrospun PVP nanofiber mats: physicochemical properties and release mechanism of α-mangostin. | Sriyanti, I., et al. 2018. Int J Nanomedicine. 13: 4927-4941. PMID: 30214198
- Anti-inflammatory therapy for preventing stroke and other vascular events after ischaemic stroke or transient ischaemic attack. | Coveney, S., et al. 2020. Cochrane Database Syst Rev. 5: CD012825. PMID: 32392374
- Concomitant Use of NSAIDs or SSRIs with NOACs Requires Monitoring for Bleeding. | Lee, MT., et al. 2020. Yonsei Med J. 61: 741-749. PMID: 32882758
- `Risk of cardiovascular disease associated with febuxostat versus allopurinol use in patients with gout: a retrospective cohort study in Korea. | Jeong, H., et al. 2023. Rheumatol Int. 43: 265-281. PMID: 36346443
- ROS-lowering doses of vitamins C and A accelerate malignant melanoma metastasis. | Kashif, M., et al. 2023. Redox Biol. 60: 102619. PMID: 36774779
- Anti-inflammatory, analgesic and ulcerogenic properties of S-(+)-ibuproxam, racemic ibuproxam-beta-cyclodextrin and S-(+)-ibuproxam-beta-cyclodextrin. | Bole-Vunduk, B., et al. 1996. J Pharm Pharmacol. 48: 1153-7. PMID: 8961164
- Compatibility study between ibuproxam and pharmaceutical excipients using differential scanning calorimetry, hot-stage microscopy and scanning electron microscopy. | Mura, P., et al. 1998. J Pharm Biomed Anal. 18: 151-63. PMID: 9863953
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ibuproxam, 100 mg | sc-471430 | 100 mg | $156.00 |