Ibufenac Acyl-β-D-Glucuronide (CAS 164669-89-0)

Ibufenac Acyl-β-D-Glucuronide is a compound that is pertinent to studies in the field of chemical metabolism, particularly concerning the glucuronidation process, which is a major pathway for the biotransformation of various lipophilic xenobiotics and endogenous substances. This compound represents a conjugated metabolite of ibufenac. In research focused on chemical metabolism, Ibufenac Acyl-β-D-Glucuronide is utilized to examine the activity and specificity of the enzyme UDP-glucuronosyltransferase (UGT), which catalyzes the transfer of glucuronic acid from uridine diphosphate glucuronic acid (UDPGA) to substrates, thus increasing their solubility and facilitating excretion. Additionally, Ibufenac Acyl-β-D-Glucuronide serves as an analytical standard in the development and validation of bioanalytical methods such as mass spectrometry and high-performance liquid chromatography (HPLC), which are essential for the detection and quantification of chemical metabolites in biological samples.