Hypoxanthine disodium salt (CAS 199329-61-8)

Hypoxanthine disodium salt is a compound in biochemical and molecular biology. It is a key substrate in the study of purine metabolism and is utilized to understand the enzymatic pathways involved in the synthesis and degradation of nucleotides. In cultures of cells and tissues, hypoxanthine disodium salt is incorporated into growth media as a purine source, necessary for nucleic acid synthesis during cell proliferation. Hypoxanthine disodium salt plays a role in the salvage pathways that recycle purines, which is a subject of interest in understanding cellular economy and genetic disorders related to purine metabolism. In molecular biology, hypoxanthine disodium salt is in selection media for the identification of cells with specific genetic traits, such as in the HAT (hypoxanthine-aminopterin-thymidine) medium in hybridoma technology for monoclonal antibody production. The salt form increases the solubility of hypoxanthine in aqueous solutions, facilitating its use in various experimental protocols.