Molecular structure of Hypoestoxide, Hypoestes rosea, CAS Number: 88498-46-8
Hypoestoxide, Hypoestes rosea (CAS 88498-46-8)
Application:
Hypoestoxide, Hypoestes rosea is a naturally occurring, cell-permeable diterpene
CAS Number:
88498-46-8
Molecular Weight:
376.49
Molecular Formula:
C22H32O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hypoestoxide, Hypoestes rosea is a naturally occurring, cell-permeable diterpene with anti-inflammatory properties. Hypoestoxide, Hypoestes rosea is a selective and direct IKK (IkappaB kinase) inhibitor in TNF-alpha stimulated HeLa cells, which prevents NF-kappaB activation. Hypoestoxide, Hypoestes rosea also inhibits the nitric oxide production by IL-1beta or IL-17 stimulated chondrocytes.
Hypoestoxide, Hypoestes rosea (CAS 88498-46-8) References
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- Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson's disease. | Kim, C., et al. 2015. J Neuroinflammation. 12: 236. PMID: 26683203
- Hypofolins A - L, ent-Labdane Diterpenoids from the Roots of Hypoestes phyllostachya 'Pink Splash'. | Cheng, B., et al. 2018. Chem Biodivers. 15: e1800124. PMID: 29667782
- The verticillenes. Pivotal intermediates in the biosynthesis of the taxanes and the phomactins. | Palframan, MJ. and Pattenden, G. 2019. Nat Prod Rep. 36: 108-121. PMID: 29978865
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- Phytochemical analysis and toxicological evaluation of the ethanolic Leaves extract of Hypoestes rosea on the morphology and biochemical indices of the Kidneys of albino Wistar Rats. | Emeribe, AU., et al. 2021. Saudi J Biol Sci. 28: 6748-6755. PMID: 34866973
Inhibitor of:
Angiogenesis, and IKK.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hypoestoxide, Hypoestes rosea, 1 mg | sc-221735 | 1 mg | $208.00 |