Hyodeoxycholic acid (CAS 83-49-8)
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Hyodeoxycholic acid is a bile acid that functions as a chemical chaperone in protein folding and stabilization. It interacts with proteins to assist in their proper folding and prevent misfolding, aggregation, or degradation. At the molecular level, it binds to specific sites on proteins, promoting their correct conformation and stability. This interaction helps to maintain the functional structure of proteins, ensuring their proper activity within experimental systems. Hyodeoxycholic acid may modulate lipid metabolism and transport, influencing the cellular uptake and utilization of lipids. Its mechanism of action involves the regulation of lipid-related pathways and processes, contributing to the metabolic balance. Hyodeoxycholic acid may play a role in protein folding and lipid metabolism, impacting the molecular and cellular functions within development applications.
Hyodeoxycholic acid (CAS 83-49-8) References
- Fecal Hyodeoxycholic Acid Is Correlated With Tylosin-Induced Microbiome Changes in Growing Pigs. | Trudeau, MP., et al. 2018. Front Vet Sci. 5: 196. PMID: 30211174
- The effects of dietary supplementation with hyodeoxycholic acid on the differentiation and function of enteroendocrine cells and the serum biochemical indices in weaned piglets. | Zong, E., et al. 2019. J Anim Sci.. PMID: 30753616
- The effects of dietary supplementation with hyodeoxycholic acid on the differentiation and function of enteroendocrine cells and the serum biochemical indices in weaned piglets1. | Zong, E., et al. 2019. J Anim Sci.. PMID: 30852589
- Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro. | Li, CX., et al. 2019. Neural Regen Res. 14: 1941-1949. PMID: 31290452
- Decrease in major secondary bile acid, hyodeoxycholic acid, was the main alteration in hepatic bile acid compositions in a hypertensive nonalcoholic fatty liver disease model. | Kodama, M., et al. 2019. J Hepatobiliary Pancreat Sci. 26: 557-567. PMID: 31562685
- Hyodeoxycholic acid (HDCA) suppresses intestinal epithelial cell proliferation through FXR-PI3K/AKT pathway, accompanied by alteration of bile acids metabolism profiles induced by gut bacteria. | Song, M., et al. 2020. FASEB J. 34: 7103-7117. PMID: 32246800
- Hyodeoxycholic acid inhibits lipopolysaccharide-induced microglia inflammatory responses through regulating TGR5/AKT/NF-κB signaling pathway. | Zhu, H., et al. 2022. J Psychopharmacol. 36: 849-859. PMID: 35475391
- Hyodeoxycholic Acid (HDCA) Prevents Development of Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice: Possible Role of Synergism between DSS and HDCA in Increasing Fecal Bile Acid Levels. | Watanabe, S., et al. 2022. Biol Pharm Bull. 45: 1503-1509. PMID: 36184509
- Alginate Alleviates Dextran Sulfate Sodium-Induced Colitis by Promoting Bifidobacterium animalis and Intestinal Hyodeoxycholic Acid Synthesis in Mice. | Pi, Y., et al. 2022. Microbiol Spectr. 10: e0297922. PMID: 36219101
- Gut microbial metabolite hyodeoxycholic acid targets the TLR4/MD2 complex to attenuate inflammation and protect against sepsis. | Li, J., et al. 2023. Mol Ther. 31: 1017-1032. PMID: 36698311
- Metagenomic and targeted metabolomic analyses reveal distinct phenotypes of the gut microbiota in patients with colorectal cancer and type 2 diabetes mellitus. | Yang, Y., et al. 2023. Chin Med J (Engl).. PMID: 36959686
- A Novel Drug Delivery System: Hyodeoxycholic Acid-Modified Metformin Liposomes for Type 2 Diabetes Treatment. | Hu, M., et al. 2023. Molecules. 28: PMID: 36985444
- Hyodeoxycholic acid attenuates cholesterol gallstone formation via modulation of bile acid metabolism and gut microbiota. | Shen, S., et al. 2023. Eur J Pharmacol. 175891. PMID: 37429516
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hyodeoxycholic acid, 5 g | sc-215161 | 5 g | $68.00 |