Hygrine (CAS 496-49-1)
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Hygrine, a derivative of pyrrolidine alkaloid, is a chemical compound that naturally occurs in the roots of specific plants, including the Hygrine officinalis shrub. This alkaloid has garnered attention for its biochemical and physiological effects, prompting investigations into its potential applications in laboratory research. Notably, hygrine exhibits properties such as anti-cancer, anti-inflammatory, and antioxidant effects in vitro. Moreover, hygrine has been used in the research of neurological disorders like epilepsy and Parkinson′s disease, as well as mental health conditions like depression and anxiety. The precise mechanism of action of hygrine remains incompletely understood. However, it is hypothesized that its effects on the central nervous system involve the modulation of specific neurotransmitters, including serotonin, norepinephrine, and dopamine.
Hygrine (CAS 496-49-1) References
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- Application of hygrine and cuscohygrine as possible markers to distinguish coca chewing from cocaine abuse on WDT and forensic cases. | Rubio, NC., et al. 2014. Forensic Sci Int. 243: 30-4. PMID: 24656326
- Possibilities for discrimination between chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios. | Rubio, NC., et al. 2015. Int J Legal Med. 129: 69-84. PMID: 25138383
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- Behaviour of hygrine and cuscohygrine in illicit cocaine production establishes their use as markers for chewing coca leaves in contrast with cocaine abuse. | Rubio, NC., et al. 2017. Drug Test Anal. 9: 323-326. PMID: 27004438
- Discrimination between chewing of coca leaves or drinking of coca tea and smoking of 'paco' (coca paste) by hair analysis. A preliminary study of possibilities and limitations. | Rubio, NC., et al. 2019. Forensic Sci Int. 297: 171-176. PMID: 30798102
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hygrine, 2.5 mg | sc-488263 | 2.5 mg | $510.00 | |||
Hygrine, 100 mg | sc-488263A | 100 mg | $18360.00 |