Date published: 2025-10-3

1-800-457-3801

SCBT Portrait Logo
Seach Input

Hydroxyzine Dihydrochloride (CAS 2192-20-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Alamon; Aterax; Durrax; Orgatrax
Application:
Hydroxyzine Dihydrochloride is a hetercyclic H1 receptor antagonist
CAS Number:
2192-20-3
Purity:
≥98%
Molecular Weight:
447.83
Molecular Formula:
C21H27ClN2O22HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Hydroxyzine Dihydrochloride is a compound that functions as a potent antagonist of histamine H1 receptors. It acts by binding to these receptors, thereby preventing the binding of histamine and subsequent activation of the receptor. This interaction inhibits the physiological effects of histamine, such as vasodilation, increased vascular permeability, and bronchoconstriction. By blocking the H1 receptors, Hydroxyzine Dihydrochloride effectively mitigates the allergic response mediated by histamine. It may possess anxiolytic properties, likely due to its ability to antagonize H1 receptors in the central nervous system. Hydroxyzine Dihydrochloride′s mode of action involves interfering with the signaling pathways activated by histamine, ultimately leading to the suppression of allergic symptoms and anxiety.


Hydroxyzine Dihydrochloride (CAS 2192-20-3) References

  1. [Hydroxyzine (atarax) neuropsychic regulator for premedication in neurosurgery].  |  BOZZA, M. and GHEZZI, R. 1956. Minerva Anestesiol. 22: 302-6. PMID: 13386991
  2. Hydroxyzine hydrochloride (atarax); a new tranquilizer.  |  ROBINSON, HM., et al. 1957. South Med J. 50: 1282-5; discussion 1285-7. PMID: 13486261
  3. Management of emotional disturbances; use of hydroxyzine (atarax) in general practice.  |  DOLAN, CM. 1958. Calif Med. 88: 443-4. PMID: 13536863
  4. Hydroxyzine (atarax) in chronic urticaria and in allergic manifestations; clinical observations in man and experimental studies on asthma in guinea pigs produced by several agents.  |  FEINBERG, AR., et al. 1958. J Allergy. 29: 358-61. PMID: 13563068
  5. An investigation into the therapeutic action of hydroxyzine (atarax) in the treatment of nervous disorders and the control of the tobacco-habit.  |  TURLE, GC. 1958. J Ment Sci. 104: 826-33. PMID: 13588340
  6. Antispasmodic properties of hydroxyzine (atarax).  |  SHERROD, TR. 1959. Toxicol Appl Pharmacol. 1: 162-7. PMID: 13635686
  7. Hydroxyzine (atarax) in the treatment of non-institutionalized psychotics.  |  REDER, EL. 1960. Dis Nerv Syst. 21: 463-6. PMID: 13740199
  8. Skin reaction to hydroxyzine (Atarax): patch test utility.  |  Dalmau, J., et al. 2006. Contact Dermatitis. 54: 216-7. PMID: 16650100

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydroxyzine Dihydrochloride, 5 g

sc-205716
5 g
$77.00

Hydroxyzine Dihydrochloride, 10 g

sc-205716A
10 g
$105.00