Molecular structure of Hydroxyzine, CAS Number: 68-88-2
Hydroxyzine (CAS 68-88-2)
Alternate Names:
2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol; 1-(p-Chloro-?-phenylbenzyl)-4-[2-(2-hydroxyethoxy)ethyl)]piperazine; Hydroxizine; Hydroxyzin; Tran-Q; Tranquizine; NSC 169188; U.C.B 4492
Application:
Hydroxyzine is an H1 receptor antagonist
CAS Number:
68-88-2
Molecular Weight:
374.90
Molecular Formula:
C21H27ClN2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
An H1 receptor antagonist. Anxiolytic and antihistaminic.
Hydroxyzine (CAS 68-88-2) References
- Hydroxyzine-induced supraventricular tachycardia in a nine-year-old child. | Wong, AR. and Rasool, AH. 2004. Singapore Med J. 45: 90-2. PMID: 14985850
- Hydroxyzine from topical phospholipid liposomal formulations: evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model. | Elzainy, AA., et al. 2003. AAPS PharmSci. 5: E28. PMID: 15198516
- Dexmedetomidine and hydroxyzine synergistically potentiate the hypnotic activity of propofol in mice. | Kimura-Kuroiwa, K., et al. 2012. J Anesth. 26: 422-8. PMID: 22349749
- Hydroxyzine distribution in postmortem cases and potential for redistribution. | McIntyre, IM., et al. 2013. Forensic Sci Int. 231: 28-33. PMID: 23890613
- Pharmacokinetics of hydroxyzine and cetirizine following oral administration of hydroxyzine to exercised Thoroughbred horses. | Knych, HK., et al. 2019. J Vet Pharmacol Ther. 42: 617-623. PMID: 31490561
- Plasma and urine pharmacokinetics of hydroxyzine and cetirizine following repeated oral administrations to exercised horses. | Paine, SW., et al. 2022. J Vet Pharmacol Ther. 45: 46-53. PMID: 34469007
- Evaluation of the Effect of Hydroxyzine on Preoperative Anxiety and Anesthetic Adequacy in Children: Double Blind Randomized Clinical Trial. | Aleo, E., et al. 2021. Biomed Res Int. 2021: 7394042. PMID: 34805403
- Hydroxyzine for lowering patient's anxiety during prehospital morphine analgesia: A prospective randomized double blind study. | Houze-Cerfon, CH., et al. 2021. Am J Emerg Med. 50: 753-757. PMID: 34879499
- A retrospective comparison of haloperidol and hydroxyzine combination therapy with haloperidol alone in the treatment of overactive delirium. | Sato, J. and Tanaka, R. 2022. Support Care Cancer. 30: 4889-4896. PMID: 35166899
- A compilation of LD50 values in newborn and adult animals. | Goldenthal, EI. 1971. Toxicol Appl Pharmacol. 18: 185-207. PMID: 5542824
Inhibitor of:
Histamine H1 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydroxyzine, 500 mg | sc-207748 | 500 mg | $320.00 |