Date published: 2026-3-22

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Hydroxytyrosol acetate (CAS 69039-02-7)

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Alternate Names:
Hydroxytyrosol acetate also known as 2-(3,4-Dihydroxyphenyl)ethyl Acetate; 4-[2-(Acetyloxy)ethyl]-1,2-benzenediol; Hydroxytyrosol Acetate; Hydroxytyrosol α-Acetate
Application:
Hydroxytyrosol acetate is an antioxidant comparable to Resveratrol and has been found in olive oil with antioxidant activity
CAS Number:
69039-02-7
Purity:
≥98%
Molecular Weight:
196.20
Molecular Formula:
C10H12O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hydroxytyrosol acetate is widely used in research that explores its antioxidant properties, particularly in the study of oxidative stress and its impact on cellular mechanisms. This compound is valuable for its potential in understanding how antioxidants can influence the stability and integrity of biological molecules in various oxidative environments. Research involving Hydroxytyrosol acetate often focuses on its efficacy in scavenging reactive oxygen species, which plays a significant role in the study of aging and chronic diseases. Additionally, it is used in studies aimed at elucidating the biochemical pathways through which antioxidants exert their effects at the molecular level. Hydroxytyrosol acetate also serves as a model compound in studies investigating the conversion mechanisms of phenolic compounds in biological systems.


Hydroxytyrosol acetate (CAS 69039-02-7) References

  1. Antioxidant activity of hydroxytyrosol acetate compared with that of other olive oil polyphenols.  |  Gordon, MH., et al. 2001. J Agric Food Chem. 49: 2480-5. PMID: 11368623
  2. Effects of hydroxytyrosol and hydroxytyrosol acetate administration to rats on platelet function compared to acetylsalicylic acid.  |  González-Correa, JA., et al. 2008. J Agric Food Chem. 56: 7872-6. PMID: 18707113
  3. Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia-reoxygenation.  |  González-Correa, JA., et al. 2008. Neurosci Lett. 446: 143-6. PMID: 18809463
  4. Distribution of hydroxytyrosol and hydroxytyrosol acetate in olive oil emulsions and their antioxidant efficiency.  |  Lisete-Torres, P., et al. 2012. J Agric Food Chem. 60: 7318-25. PMID: 22720906
  5. Protective activity of hydroxytyrosol metabolites on erythrocyte oxidative-induced hemolysis.  |  Paiva-Martins, F., et al. 2013. J Agric Food Chem. 61: 6636-42. PMID: 23777263
  6. Gender differences in plasma and urine metabolites from Sprague-Dawley rats after oral administration of normal and high doses of hydroxytyrosol, hydroxytyrosol acetate, and DOPAC.  |  Domínguez-Perles, R., et al. 2017. Eur J Nutr. 56: 215-224. PMID: 26463517
  7. Antibacterial Activity of Hydroxytyrosol Acetate from Olive Leaves (Olea Europaea L.).  |  Wei, J., et al. 2018. Nat Prod Res. 32: 1967-1970. PMID: 28768425
  8. The protective effect of hydroxytyrosol acetate against inflammation of vascular endothelial cells partly through the SIRT6-mediated PKM2 signaling pathway.  |  Yao, F., et al. 2019. Food Funct. 10: 5789-5803. PMID: 31461107
  9. A Three-Step, Gram-Scale Synthesis of Hydroxytyrosol, Hydroxytyrosol Acetate, and 3,4-Dihydroxyphenylglycol.  |  Kalampaliki, AD., et al. 2019. Molecules. 24: PMID: 31492013
  10. Hydroxytyrosol Acetate Improves the Cognitive Function of APP/PS1 Transgenic Mice in ERβ-dependent Manner.  |  Qin, C., et al. 2021. Mol Nutr Food Res. 65: e2000797. PMID: 33296142
  11. Hydroxytyrosol Acetate Inhibits Vascular Endothelial Cell Pyroptosis via the HDAC11 Signaling Pathway in Atherosclerosis.  |  Yao, F., et al. 2021. Front Pharmacol. 12: 656272. PMID: 33967800
  12. Antioxidant Effect of Hydroxytyrosol, Hydroxytyrosol Acetate and Nitrohydroxytyrosol in a Rat MPP+ Model of Parkinson's Disease.  |  Pérez-Barrón, G., et al. 2021. Neurochem Res. 46: 2923-2935. PMID: 34260002
  13. De novo biosynthesis of tyrosol acetate and hydroxytyrosol acetate from glucose in engineered Escherichia coli.  |  Guo, D., et al. 2021. Enzyme Microb Technol. 150: 109886. PMID: 34489039
  14. Influence of Hydroxytyrosol Acetate Enrichment of an Oil Rich in Omega-6 Groups on the Evolution of Its Oxidation and Oxylipin Formation When Subjected to Accelerated Storage. A Global Study by Proton Nuclear Magnetic Resonance.  |  Caño-Ochoa, SD., et al. 2022. Antioxidants (Basel). 11: PMID: 35453407
  15. Individual and Joint Effect of Alpha-Tocopherol and Hydroxytyrosol Acetate on the Oxidation of Sunflower Oil Submitted to Oxidative Conditions: A Study by Proton Nuclear Magnetic Resonance.  |  Caño-Ochoa, SD., et al. 2022. Antioxidants (Basel). 11: PMID: 35740054

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydroxytyrosol acetate, 50 mg

sc-488930
50 mg
$152.00

Hydroxytyrosol acetate, 100 mg

sc-488930C
100 mg
$271.00

Hydroxytyrosol acetate, 250 mg

sc-488930A
250 mg
$658.00

Hydroxytyrosol acetate, 2.5 g

sc-488930B
2.5 g
$2539.00