Date published: 2025-12-25

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Hydroxylamine-O-sulfonic acid (CAS 2950-43-8)

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CAS Number:
2950-43-8
Purity:
≥97%
Molecular Weight:
113.09
Molecular Formula:
H3NO4S
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hydroxylamine-O-sulfonic acid is a compound that is in biochemistry. It is a derivative of hydroxylamine and is utilized as a reagent in various chemical reactions. Hydroxylamine-O-Sulfonic Acid is for its ability to act as a reducing agent, particularly in the conversion of nitro compounds to amines. It is also in the preparation of oximes from carbonyl compounds. Hydroxylamine-O-sulfonic acid is particularly useful in the synthesis of agrochemicals. Its unique properties make it important in the field of biochemistry, allowing for the efficient and selective transformation of various functional groups in organic molecules. Hydroxylamine-O-sulfonic acid plays a role in the development and production of a wide range of chemical products.


Hydroxylamine-O-sulfonic acid (CAS 2950-43-8) References

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  2. Mechanism of metal-mediated DNA damage induced by metabolites of carcinogenic 2-nitropropane.  |  Sakano, K., et al. 2001. Mutat Res. 479: 101-11. PMID: 11470485
  3. Synthesis and chemistry of 3-tert-butyl-1,5-diaminopyrazole.  |  Blake, AJ., et al. 2003. Org Biomol Chem. 1: 4268-74. PMID: 14685330
  4. Hydroxylamine-O-sulfonic acid as an efficient coreactant for luminol chemiluminescence for selective and sensitive detection.  |  Saqib, M., et al. 2015. Chem Commun (Camb). 51: 6536-9. PMID: 25766485
  5. Energetic 2,2-Dimethyltriazanium Salts: A New Family of Nitrogen-Rich Hydrazine Derivatives.  |  Forquet, V., et al. 2015. Chem Asian J. 10: 1668-75. PMID: 25975814
  6. Direct and Stereospecific Synthesis of N-H and N-Alkyl Aziridines from Unactivated Olefins Using Hydroxylamine-O-Sulfonic Acids.  |  Ma, Z., et al. 2017. Angew Chem Int Ed Engl. 56: 9886-9890. PMID: 28614619
  7. O-Substituted hydroxyl amine reagents: an overview of recent synthetic advances.  |  Sabir, S., et al. 2018. Org Biomol Chem. 16: 3314-3327. PMID: 29645045
  8. Chemiluminescence assay for Listeria monocytogenes based on Cu/Co/Ni ternary nanocatalyst coupled with penicillin as generic capturing agent.  |  Zhang, Y., et al. 2021. Luminescence. 36: 11-19. PMID: 32602594
  9. Cu(OTf)2-catalyzed Beckmann Rearrangement of Ketones Using Hydroxylamine-O-sulfonic Acid (HOSA).  |  Munnuri, S., et al. 2019. Synthesis (Stuttg). 51: 3709-3714. PMID: 32684655
  10. Rapid 'on-column' preparation of hydrogen [11C]cyanide from [11C]methyl iodide via [11C]formaldehyde.  |  Kikuchi, T., et al. 2022. Chem Sci. 13: 3556-3562. PMID: 35432866
  11. Aminations of guanosine and deoxyguanosine with hydroxylamine-O-sulfonic acid and 2,4-dinitrophenoxyamine. Dependence on the reaction medium.  |  Kohda, K., et al. 1986. Nucleic Acids Symp Ser. 145-8. PMID: 3562259
  12. Site-selective amination and/or nitrilation via metal-free C(sp2)-C(sp3) cleavage of benzylic and allylic alcohols.  |  Anugu, RR. and Falck, JR. 2022. Chem Sci. 13: 4821-4827. PMID: 35655896
  13. Cu-α-diimine Compounds Encapsulated in Porous Materials as Catalysts for Electrophilic Amination of Aromatic C-H Bonds.  |  Van Emelen, L., et al. 2022. ACS Appl Mater Interfaces. 14: 51867-51880. PMID: 36349551
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydroxylamine-O-sulfonic acid, 5 g

sc-250138
5 g
$32.00

Hydroxylamine-O-sulfonic acid, 25 g

sc-250138A
25 g
$72.00