Molecular structure of Hydroxyhomo Sildenafil, CAS Number: 139755-85-4
Hydroxyhomo Sildenafil (CAS 139755-85-4)
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Alternate Names:
Lodenafil
Application:
Hydroxyhomo Sildenafil is An analog of Sildenafil and a potential PDE5 inhibitor
CAS Number:
139755-85-4
Purity:
≥97%
Molecular Weight:
504.60
Molecular Formula:
C23H32N6O5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hydroxyhomo Sildenafil is an analog of Sildenafil (sc-338584). Hydroxyhomo Sildenafil serves as a tool for studying the biochemical and pharmacological properties of PDE5 inhibitors. It allows researchers to compare its effects with those of Sildenafil, enhancing our understanding of how structural differences influence binding affinity and enzyme inhibition.
Hydroxyhomo Sildenafil (CAS 139755-85-4) References
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- Phosphodiesterase type 5 inhibitor differentiation based on selectivity, pharmacokinetic, and efficacy profiles. | Seftel, AD. 2004. Clin Cardiol. 27: I14-19. PMID: 15115191
- The role of sildenafil in the treatment of stroke. | Bednar, MM. 2008. Curr Opin Investig Drugs. 9: 754-9. PMID: 18600581
- Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small-intestinal ulceration in rats via a NO/cGMP-dependent mechanism. | Kato, N., et al. 2009. Dig Dis Sci. 54: 2346-56. PMID: 19101800
- Structure elucidation of phototransformation products of unapproved analogs of the erectile dysfunction drug sildenafil in artificial freshwater with UPLC-Q Exactive-MS. | Aceña, J., et al. 2014. J Mass Spectrom. 49: 1279-89. PMID: 25476946
- Development and evaluation of an immunochromatographic strip for rapid screening of sildenafil-type compounds as illegal additives in functional foods. | Guo, J., et al. 2016. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 33: 1095-104. PMID: 27310564
- Rapid detection of six phosphodiesterase type 5 enzyme inhibitors in healthcare products using thin-layer chromatography and surface enhanced Raman spectroscopy combined with BP neural network. | Hu, X., et al. 2017. J Sep Sci. 40: 2506-2514. PMID: 28436147
- An immunochromatographic strip sensor for sildenafil and its analogues. | Wang, Z., et al. 2019. J Mater Chem B. 7: 6383-6389. PMID: 31642841
- Simultaneous analysis of 31 anti-impotence compounds potentially illegally added to herbal-based dietary supplements by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. | Shi, S., et al. 2020. J Chromatogr B Analyt Technol Biomed Life Sci. 1144: 122077. PMID: 32251992
- Rapid Screening and Quantitative Determination of Illegal Phosphodiesterase Type 5 Inhibitors (PDE-5i) in Herbal Dietary Supplements. | Nguyen, TO., et al. 2021. J Anal Methods Chem. 2021: 5579500. PMID: 34035975
- Fast and semiquantitative screening for sildenafil in herbal over-the-counter formulations with atmospheric pressure solid analysis probe (ASAP) to prevent medicinal adulteration. | Moser, D., et al. 2022. J Pharm Biomed Anal. 214: 114720. PMID: 35286987
- Detection of 94 PDE-5is and Their Analogs Including N-Desmethylthiosildenafil in Various Formulations of Dietary Supplements and Food Samples Using HPLC and LC-Q-TOF/MS. | Lee, JH., et al. 2022. J Chromatogr Sci. 60: 953-962. PMID: 35535451
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydroxyhomo Sildenafil, 5 mg | sc-211615 | 5 mg | $326.00 | |||
Hydroxyhomo Sildenafil, 10 mg | sc-211615A | 10 mg | $500.00 |