Molecular structure of Hydroxy Bupropion-d6, CAS Number: 1216893-18-3
Hydroxy Bupropion-d6 (CAS 1216893-18-3)
See product citations (3)
Alternate Names:
2-Hydroxy-2-(3′-chlorophenyl)-3,5,5-trimethylmorpholine-d6
Application:
Hydroxy Bupropion-d6 is a useful labeled metabolite of Bupropion (sc-211604)
CAS Number:
1216893-18-3
Purity:
≥97%
Molecular Weight:
261.78
Molecular Formula:
C13H12D6ClNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hydroxy Bupropion-d6 is a useful labeled metabolite of Bupropion (sc-211604). Hydroxy Bupropion-d6 is a stable-labeled compound designed as an internal standard for quantifying levels of hydroxybupropion in urine, serum, or plasma samples using LC/MS or GC/MS techniques. It serves as useful in various applications, including urine drug testing, clinical toxicology, forensic analysis, and isotope dilution methods.
Hydroxy Bupropion-d6 (CAS 1216893-18-3) References
- Metabolism of some 'second'- and 'fourth'-generation antidepressants: iprindole, viloxazine, bupropion, mianserin, maprotiline, trazodone, nefazodone, and venlafaxine. | Rotzinger, S., et al. 1999. Cell Mol Neurobiol. 19: 427-42. PMID: 10379419
- Ultra-performance liquid chromatography- tandem mass spectrometry method for the determination of bupropion and its main metabolites in human whole blood. | Denooz, R., et al. 2010. J Anal Toxicol. 34: 280-6. PMID: 20529462
- The application of HepRG cells in evaluation of cytochrome P450 induction properties of drug compounds. | Andersson, TB. 2010. Methods Mol Biol. 640: 375-87. PMID: 20645063
- De-risking bio-therapeutics for possible drug interactions using cryopreserved human hepatocytes. | Dallas, S., et al. 2012. Curr Drug Metab. 13: 923-9. PMID: 22475265
- Mechanism of autoinduction of methadone N-demethylation in human hepatocytes. | Campbell, SD., et al. 2013. Anesth Analg. 117: 52-60. PMID: 23733841
- Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model. | Xia, L., et al. 2016. J Appl Toxicol. 36: 320-9. PMID: 26201057
- The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes. | Liu, H., et al. 2016. Drug Metab Lett. 10: 195-199. PMID: 27449409
- New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery. | Ogasawara, A., et al. 2016. Drug Metab Lett. 10: 152-160. PMID: 27550199
- Stereoselective Bupropion Hydroxylation by Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase Genetic Variants. | Wang, PF., et al. 2020. Drug Metab Dispos. 48: 438-445. PMID: 32238417
- Mass spectrometric sample identification with indicator compounds introduced via labeled sample tubes. | Paal, M., et al. 2020. Clin Chem Lab Med. 59: 147-154. PMID: 32716904
- In vitro evaluation of fenfluramine and norfenfluramine as victims of drug interactions. | Martin, P., et al. 2022. Pharmacol Res Perspect. 10: e00958. PMID: 35599345
- Pharmacokinetics of bupropion and its metabolites in cigarette smokers versus nonsmokers. | Hsyu, PH., et al. 1997. J Clin Pharmacol. 37: 737-43. PMID: 9378846
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydroxy Bupropion-d6, 1 mg | sc-280795 | 1 mg | $430.00 |