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Hydroflumethiazide (CAS 135-09-1)

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Alternate Names:
3,4-Dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; Bristab; Bristurin; Dihydroflumethiazide; Diucardin; Elodrine; Finuret; Flutizide; Glomerulin; Hidroalogen; Leodrine; Saluron; Vergonil
Application:
Hydroflumethiazide is an anti-hypertensive and a diuretic
CAS Number:
135-09-1
Purity:
98%
Molecular Weight:
331.29
Molecular Formula:
C8H8F3N3O4S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hydroflumethiazide is a compound of interest within chemistry, it is studied for its physicochemical properties and interactions with various biological molecules. In analytical chemistry, hydroflumethiazide is used as a reference standard to develop and validate analytical methods for detecting and quantifying substances with similar chemical structures. Studies on hydroflumethiazide includes investigations into its stability under different environmental conditions, such as pH and temperature, which is for understanding its behavior in various systems. Studies on its solubility and permeability are pertinent to the fields of material science and environmental chemistry. The compound′s role in various chemical reactions and its interaction with other chemical agents provides insight into reaction mechanisms and pathways.


Hydroflumethiazide (CAS 135-09-1) References

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  2. FI-chemiluminometric study of thiazides by on-line photochemical reaction.  |  Ciborowski, M., et al. 2004. J Pharm Biomed Anal. 36: 693-700. PMID: 15533660
  3. Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.  |  Temperini, C., et al. 2008. Bioorg Med Chem Lett. 18: 2567-73. PMID: 18374572
  4. Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?  |  Temperini, C., et al. 2008. Org Biomol Chem. 6: 2499-506. PMID: 18600270
  5. Application of p-N,N-dimethylphenylenediamine dihydrochloride for the determination of some diuretics.  |  Sastry, CS., et al. 1989. Talanta. 36: 491-4. PMID: 18964744
  6. Probing the allosteric modulator binding site of GluR2 with thiazide derivatives.  |  Ptak, CP., et al. 2009. Biochemistry. 48: 8594-602. PMID: 19673491
  7. Rapid determination of losartan and losartan acid in human plasma by multiplexed LC-MS/MS.  |  Shah, HJ., et al. 2009. J Sep Sci. 32: 3388-94. PMID: 19750501
  8. Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning.  |  Turanli, B., et al. 2019. EBioMedicine. 42: 386-396. PMID: 30905848
  9. Amorphous spray-dried hydroflumethiazide-polyvinylpyrrolidone systems: physiochemical properties.  |  Corrigan, OI. and Holohan, EM. 1984. J Pharm Pharmacol. 36: 217-21. PMID: 6144766
  10. Absorption kinetics of hydroflumethiazide.  |  McNamara, PJ., et al. 1978. J Clin Pharmacol. 18: 190-3. PMID: 632365
  11. Comparison of derivatization procedures for the determination of diuretics in urine by gas chromatography-mass spectrometry.  |  Carreras, D., et al. 1994. J Chromatogr A. 683: 195-202. PMID: 7952012
  12. Inhibition of thiazide photohemolysis in vitro by antioxidants and a nitrogen atmosphere.  |  Selvaag, E. 1996. Photodermatol Photoimmunol Photomed. 12: 211-5. PMID: 9112280
  13. Inhibiting effects of antioxidants on drug-induced phototoxicity in cell cultures. Investigations with sulphonamide-derived oral antidiabetics and diuretics.  |  Selvaag, E., et al. 1997. J Photochem Photobiol B. 38: 88-93. PMID: 9134756
  14. Phototoxicity to sulphonamide-derived oral antidiabetics and diuretics: investigations in hairless mice.  |  Selvaag, E. and Thune, P. 1997. Photodermatol Photoimmunol Photomed. 13: 4-8. PMID: 9361121

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydroflumethiazide, 100 mg

sc-211601
100 mg
$250.00