Hydrocortisone sodium phosphate (CAS 6000-74-4)
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Hydrocortisone sodium phosphate (HSP) is a type of synthetic glucocorticoid that was developed to minimize the risk of systemic side effects typically associated with other glucocorticoids. Being water-soluble and non-esterified, it has been utilized in various fields of research, including cancer, immunology, and endocrinology, to investigate the impact of glucocorticoids on tumor growth, immune system, hormone production, and metabolism. The mechanism of action of Hydrocortisone sodium phosphate involves binding to glucocorticoid receptors, which are found in the cytoplasm of cells and are part of the nuclear hormone receptor family involved in regulating gene expression. Activation of the receptor by Hydrocortisone sodium phosphate leads to the expression of specific genes via a series of sequential events.
Hydrocortisone sodium phosphate (CAS 6000-74-4) References
- [Hydrocortisone Sodium Phosphate Reference Standard (Control 001) of National Institute of Health Sciences]. | Iwata, M., et al. 2001. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 82-5. PMID: 11915292
- In vitro iontophoretic studies using a synthetic membrane. | Tu, YH. and Allen, LV. 1989. J Pharm Sci. 78: 211-3. PMID: 2724080
- Medical treatment of inflammatory punctual stenosis monitored by anterior segment optical coherence tomography. | Elalfy, HY., et al. 2020. Int J Ophthalmol. 13: 1074-1078. PMID: 32685394
- Kinetics of hydrocortisone sodium phosphate penetration into the human aqueous humor after topical application. | Cagini, C., et al. 2021. Int J Clin Pract. 75: e14987. PMID: 34672064
- Short-term results of a pulsed therapy with hydrocortisone eye drops to treat moderate to severe dry eye in primary Sjögren syndrome patients. | Menchini, M., et al. 2023. Graefes Arch Clin Exp Ophthalmol. 261: 1029-1036. PMID: 36192456
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydrocortisone sodium phosphate, 25 mg | sc-353623A | 25 mg | $80.00 | |||
Hydrocortisone sodium phosphate, 100 mg | sc-353623B | 100 mg | $240.00 | |||
Hydrocortisone sodium phosphate, 1 g | sc-353623 | 1 g | $525.00 |