Date published: 2025-10-15

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Hydrocortisone 17-Acetate (CAS 16463-74-4)

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Alternate Names:
(11β)-17-(Acetyloxy)-11,21-dihydroxypregn-4-ene-3,20-dione; Cortisol 17-Acetate
Application:
Hydrocortisone 17-Acetate is a glucocorticoid and minor degradation product of Hydrocortisone 21-Acetate
CAS Number:
16463-74-4
Molecular Weight:
404.5
Molecular Formula:
C23H32O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hydrocortisone 17-Acetate, a synthesized variant of the natural steroid hormone cortisol, is crafted to emulate cortisol′s physiological functions while offering improved stability and solubility for research purposes. It serves as an essential resource in the study of endocrinology and inflammation, allowing researchers to delve into the actions of steroid hormones such as the modulation of gene expression, regulation of immune responses, and the cellular response to stress. This compound is instrumental in examining the molecular underpinnings of inflammation and stress responses, thereby aiding in the creation of innovative research techniques and enhancing our grasp of steroid hormone dynamics. Its ability to bind with high affinity to steroid hormone receptors makes it a precise tool for probing the intricate interplay within the endocrine system, shedding light on its influence on cellular metabolism and maintaining physiological balance.


Hydrocortisone 17-Acetate (CAS 16463-74-4) References

  1. Diffusion properties of model compounds in artificial sebum.  |  Valiveti, S. and Lu, GW. 2007. Int J Pharm. 345: 88-94. PMID: 17624701
  2. Glucocorticoid receptor binding: a biphasic dependence on molecular size as revealed by the bilinear LinBiExp model.  |  Buchwald, P. 2008. Steroids. 73: 193-208. PMID: 18022656
  3. Application of LC-MS/MS and UHPLC-Q-Orbitrap methods for determining 54 steroids in illegal dietary supplements and other sample types.  |  Lee, JH., et al. 2022. Rapid Commun Mass Spectrom. 36: e9334. PMID: 35705484
  4. Structure-activity relationships in the antiinflammatory steroids: a pattern-recognition approach.  |  Bodor, N., et al. 1983. J Med Chem. 26: 318-28. PMID: 6827553

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hydrocortisone 17-Acetate, 50 mg

sc-489985
50 mg
$380.00