Hyaluronate lyase cleaves hyaluronic acid at the β-D-GalNAc-(1→4)-β-D-GlcA bond, yielding 3-(4-deoxy-β-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine tetra- and hexasaccharides. Unlike other hyaluronidases, this enzyme is specific for hyaluronic acid and is inactive with Chondroitin and Chondroitn sulfate (sc-203888). One unit will cause a change in A600 nm of 0.330 per minute at pH 5.7 at 37° C during a 45 minute assay.
One ampule contains 300 units
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
Hyaluronidase Product Citations
See how others have used Hyaluronidase. Click on the entry to view the PubMed entry
How should the enzyme be reconstituted for long-term storage and at these conditions how long is the enzyme stable for?
Asked by: harding
Thank you for your question. The product has buffer present (it is lyophilized from 0.5 mM Tris buffer at pH 7), it is soluble in 1 mL of water and should be stored refrigerated; do not freeze since it is not known what effect freeze/thawing would have on the solutions. Unfortunately we do not have an estimate of stability time for refrigerated enzyme solutions.
Rated 4 out of
works as expectedThis hyaluronidase was cheaper and more readily available than options offered by some other companies, with same apparent enzyme activity. Documentation was not included, but technical support was very helpful in determining resuspension and storage methods.
Date published: 2017-11-06
Rated 5 out of
Yamaguchi et alYamaguchi et al. (PubMed ID 26296532) used hyaluronidase to inhibit the activity of hyaluronic acid by cleaving. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
You may not log in without verifying your email address. Please check your email (including your spam email) for the Welcome message that was sent.
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.
Already have an account?
Please check your email (including your spam email) for a Welcome message, and verify your email address to continue.