Date published: 2026-5-6

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human spleen extract: sc-363779

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Datasheets
  • 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
  • Western blotting positive control
  • recommended use is 50 µg (20 µl) per lane
  • extracts should be stored at -20°C and repeated freezing and thawing should be minimized
  • sample vial should be placed at 95° C for up to 5 minutes, once prior to use
  • Not available in Germany.
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Human spleen extract, derived from spleen tissue, serves as a valuable research tool in elucidating the complex functions of the spleen and its role in immune responses. This extract contains a diverse array of bioactive molecules, including immune cells (such as lymphocytes, macrophages, and dendritic cells), cytokines, chemokines, and extracellular matrix components, reflecting the immunomodulatory and hematopoietic functions of the spleen. Mechanistically, human spleen extract has been utilized to study immune cell differentiation, activation, and trafficking, as well as the interplay between immune cells and their microenvironment within the spleen. Researchers use this extract to investigate the development and regulation of immune responses, including the generation of adaptive immune memory, the clearance of pathogens and cellular debris, and the maintenance of immune homeostasis. Additionally, human spleen extract serves as a crucial component in in vitro models of immune cell function and immunomodulatory therapies, facilitating the study of autoimmune diseases, infectious diseases, and cancer immunotherapy. Studies employing human spleen extract contribute to our understanding of immune system biology and pathology, providing insights into novel strategies for immune-related disorders.

human spleen extract References:

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  7. Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins.  |  Garrett, MD., et al. 1989. J Biol Chem. 264: 10-3. PMID: 2491843
  8. Higher incidences of anti-SS-A/Ro and anti-SS-B/La autoantibodies in Japanese patients with autoimmune disorders--studies of antigens and antibodies using the immunoblotting method.  |  Inagaki, Y., et al. 1989. Arch Dermatol Res. 281: 89-94. PMID: 2774641
  9. Fine specificities of autoantibodies directed against the Ro, La, Sm, RNP, and Jo-1 proteins defined by two-dimensional gel electrophoresis and immunoblotting.  |  Elkon, KB. and Jankowski, PW. 1985. J Immunol. 134: 3819-24. PMID: 2985698
  10. Purification and characterization of the Sjögren's syndrome A and B antigens.  |  Venables, PJ., et al. 1983. Clin Exp Immunol. 54: 731-8. PMID: 6360447
  11. Identification and purification of a 55K polypeptide in Sjögren's syndrome A antigen.  |  Smith, PR., et al. 1984. Rheumatol Int. 4: 135-8. PMID: 6431590
  12. Phosphorylation profiles of 60 kD Ro antigen in synchronized HEp-2 cells.  |  López-Luna, A., et al. 1995. Scand J Rheumatol. 24: 293-9. PMID: 8533044
  13. IP-Heterogeneity of Nuclear Antigens Detected in an Isoelectric Focusing-Immunoblot System  |  B Kohleisen, I Kalies, K Kölble, JR Kalden. 1985. Protides of the Biological Fluids. 33: 195-198.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

human spleen extract

sc-363779
500 µg/200 µl
$120.00