human placenta extract: sc-363772

Human placenta extract is derived from the placenta, an organ that develops in the uterus during pregnancy, serving as a critical interface between the mother and the fetus. This extract is rich in a variety of bioactive molecules including hormones, growth factors, and cytokines, which are pivotal for fetal development and maternal health. The extraction process typically involves the collection of the placenta post-delivery, followed by careful purification and homogenization to isolate specific compounds. In research environments, human placenta extract provides a unique window into reproductive biology and developmental processes. Scientists utilize this extract to study the mechanisms of nutrient and oxygen transfer from mother to fetus, immune tolerance during pregnancy, and the production of hormones that regulate pregnancy and fetal development. Additionally, it is used in investigations into the repair and regeneration capabilities of placental cells, offering insights into cellular growth and healing processes. The extract has also proven valuable in exploring the complex signaling pathways that govern placental function and adaptation throughout pregnancy. By providing a concentrated source of placental components, this extract aids in deepening the understanding of not only pregnancy-related phenomena but also the broader aspects of cellular communication and growth regulation.

human placenta extract References:

1. L-tryptophan as an antioxidant in human placenta extract.  |  Watanabe, S., et al. 2002. J Nutr Sci Vitaminol (Tokyo). 48: 36-9. PMID: 12026186
2. Antioxidative collagen-derived peptides in human-placenta extract.  |  Togashi, S., et al. 2002. Placenta. 23: 497-502. PMID: 12137748
3. Isolation of plasminogen activator inhibitor-2 (PAI-2) from human placenta. Evidence for vitronectin/PAI-2 complexes in human placenta extract.  |  Radtke, KP., et al. 1990. Biol Chem Hoppe Seyler. 371: 1119-27. PMID: 1708670
4. Human placenta promotes IL-8 expression through activation of JNK/SAPK and transcription factors NF-kappaB and AP-1 in PMA-differentiated THP-1 cells.  |  Kang, SS., et al. 2007. Int Immunopharmacol. 7: 1488-95. PMID: 17761353
5. Efficacy and safety of human placenta extract in alleviating climacteric symptoms: prospective, randomized, double-blind, placebo-controlled trial.  |  Lee, YK., et al. 2009. J Obstet Gynaecol Res. 35: 1096-101. PMID: 20144174
6. Protective effects of human placenta extract on cartilage degradation in experimental osteoarthritis.  |  Kim, JK., et al. 2010. Biol Pharm Bull. 33: 1004-10. PMID: 20522967
7. The effect of human placenta extract in a wound healing model.  |  Hong, JW., et al. 2010. Ann Plast Surg. 65: 96-100. PMID: 20548228
8. Placenta extract promote liver regeneration in CCl4-injured liver rat model.  |  Jung, J., et al. 2011. Int Immunopharmacol. 11: 976-84. PMID: 21354355
9. Anti-inflammatory and analgesic effects of human placenta extract.  |  Lee, KH., et al. 2011. Nat Prod Res. 25: 1090-100. PMID: 21726131
10. Anti-stress effects of human placenta extract: possible involvement of the oxidative stress system in rats.  |  Park, HJ., et al. 2018. BMC Complement Altern Med. 18: 149. PMID: 29739458
11. Effects of Human Placenta Extract (Laennec) on Ligament Healing in a Rodent Model.  |  Shin, EH., et al. 2019. Biol Pharm Bull. 42: 1988-1995. PMID: 31787714
12. Effect of Porcine Placenta Extract Supplement on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind Placebo-Controlled Study.  |  Nagae, M., et al. 2020. Nutrients. 12: PMID: 32512710
13. Restorative effects of human placenta extract in X-ray-irradiated mice.  |  Mochizuki, H. and Kada, T. 1982. J Radiat Res. 23: 403-10. PMID: 7161751