HTLV-2 p24 Antibody (75/4.21.11): sc-57876

HTLV-2 p24 Antibody (75/4.21.11) is a mouse monoclonal IgG1 antibody that detects the HTLV-2 p24 protein of HTLV-2 origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-HTLV-2 p24 antibody (75/4.21.11) is available as the non-conjugated format. HTLV-2 p24 plays a crucial role in the viral life cycle as a major structural component of the virus′s core, which is essential for the assembly and release of new viral particles. Understanding HTLV-2 p24 function is important because this protein not only aids in virus identification but also serves as a target for therapeutic interventions aimed at preventing the progression of HTLV-2-related diseases, such as tropical spastic paraparesis and other neurological disorders. Human T-lymphotropic virus (HTLV) is a single-stranded RNA retrovirus that can lead to T-cell leukemia and T-cell lymphoma in adults, and HTLV-2 shares approximately 70% genomic homology with HTLV-1, which is associated with various diseases including HTLV-I-associated myelopathy. Differential antibody responsiveness to p19 gag can be utilized for serological discrimination between HTLV-1 and HTLV-2, highlighting the significance of HTLV-2 p24 monoclonal antibody (75/4.21.11) in both research and clinical diagnostics.

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HTLV-2 p24 Antibody (75/4.21.11) References:

1. Envelope is a major viral determinant of the distinct in vitro cellular transformation tropism of human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2.  |  Xie, L. and Green, PL. 2005. J Virol. 79: 14536-45. PMID: 16282453
2. Human T lymphotropic virus types I and II western blot seroindeterminate status and its association with exposure to prototype HTLV-I.  |  Yao, K., et al. 2006. J Infect Dis. 193: 427-37. PMID: 16388491
3. Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo.  |  Hiraragi, H., et al. 2006. J Virol. 80: 3469-76. PMID: 16537614
4. Human T-cell leukemia virus (HTLV) in the United Kingdom.  |  Greaves, MF., et al. 1984. Int J Cancer. 33: 795-806. PMID: 6329969
5. Production and characterization of a monoclonal antibody directed against HTLV-1 p19: use in a specific capture enzyme immunoassay.  |  Ebersold, A., et al. 1993. Hybridoma. 12: 185-95. PMID: 7686136
6. [Molecular characterization of human T-cell lymphotrophic virus type II].  |  Takahashi, H. 1993. Hokkaido Igaku Zasshi. 68: 485-95. PMID: 8340046
7. Assessment of a new immunoassay for serological confirmation and discrimination of human T-cell lymphotropic virus infections.  |  Zrein, M., et al. 1998. Clin Diagn Lab Immunol. 5: 45-9. PMID: 9455879
8. Differential antibody responsiveness to p19 gag results in serological discrimination between human T lymphotropic virus type I and type II.  |  Lal, RB., et al. 1991. J Med Virol. 35: 232-6. PMID: 1687064
9. Substrates and inhibitors of human T-cell leukemia virus type I protease.  |  Ding, YS., et al. 1998. Biochemistry. 37: 17514-8. PMID: 9860866

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HTLV-2 p24 Antibody (75/4.21.11) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HTLV-2 p24 Antibody (75/4.21.11) Specifications

Alternate Product Name: HTLV-2 p24

Product Clone Name: 75/4.21.11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: HTLV-2 p24

Epitope Species: HTLV-2

Product Reactivity/Detection: HTLV-2 p24

Species Reactivity/Detection: HTLV-2

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for HTLV-2 p24 Antibody (75/4.21.11): N/A