HTLV-1 p19 Antibody (45/6.11.1.3): sc-57868

HTLV-1 p19 Antibody (45/6.11.1.3) is a mouse monoclonal IgG1 antibody that detects the HTLV-1 p19 protein of HTLV-1 origin by western blotting (WB) and immunofluorescence (IF). HTLV-1 p19 (45/6.11.1.3) monoclonal antibody is available as the non-conjugated format, providing researchers with a reliable tool for studying this important viral protein. HTLV-1 p19 plays a crucial role in the viral life cycle as a major core protein encoded by the gag gene, which is essential for the assembly and release of viral particles. Understanding p19′s function is vital, as p19 not only contributes to the structural integrity of the virus but also influences the immune response in infected individuals. The ability to differentiate between HTLV-1 and HTLV-2 through antibody responsiveness to p19 gag is significant for clinical diagnostics and epidemiological studies, as HTLV-1 is associated with various diseases, including T-cell leukemia and HTLV-1-associated myelopathy. The transmission routes of HTLV-1, which include sexual contact, childbirth, and exposure to contaminated blood, underscore the importance of studying p19 in the context of public health and disease prevention.

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HTLV-1 p19 Antibody (45/6.11.1.3) References:

1. Envelope is a major viral determinant of the distinct in vitro cellular transformation tropism of human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2.  |  Xie, L. and Green, PL. 2005. J Virol. 79: 14536-45. PMID: 16282453
2. Human T lymphotropic virus types I and II western blot seroindeterminate status and its association with exposure to prototype HTLV-I.  |  Yao, K., et al. 2006. J Infect Dis. 193: 427-37. PMID: 16388491
3. Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo.  |  Hiraragi, H., et al. 2006. J Virol. 80: 3469-76. PMID: 16537614
4. Differential antibody responsiveness to p19 gag results in serological discrimination between human T lymphotropic virus type I and type II.  |  Lal, RB., et al. 1991. J Med Virol. 35: 232-6. PMID: 1687064
5. Human T-cell leukemia virus (HTLV) in the United Kingdom.  |  Greaves, MF., et al. 1984. Int J Cancer. 33: 795-806. PMID: 6329969
6. Production and characterization of a monoclonal antibody directed against HTLV-1 p19: use in a specific capture enzyme immunoassay.  |  Ebersold, A., et al. 1993. Hybridoma. 12: 185-95. PMID: 7686136
7. [Molecular characterization of human T-cell lymphotrophic virus type II].  |  Takahashi, H. 1993. Hokkaido Igaku Zasshi. 68: 485-95. PMID: 8340046
8. Assessment of a new immunoassay for serological confirmation and discrimination of human T-cell lymphotropic virus infections.  |  Zrein, M., et al. 1998. Clin Diagn Lab Immunol. 5: 45-9. PMID: 9455879
9. Substrates and inhibitors of human T-cell leukemia virus type I protease.  |  Ding, YS., et al. 1998. Biochemistry. 37: 17514-8. PMID: 9860866

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HTLV-1 p19 Antibody (45/6.11.1.3) has 1 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HTLV-1 p19 Antibody (45/6.11.1.3) Specifications

Alternate Product Name: HTLV-1 p19

Product Clone Name: 45/6.11.1.3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: HTLV-1 p19

Epitope Species: HTLV-1

Product Reactivity/Detection: HTLV-1 p19

Species Reactivity/Detection: HTLV-1

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for HTLV-1 p19 Antibody (45/6.11.1.3): N/A