HT-1080 Whole Cell Lysate: sc-364183

HT-1080 Whole Cell Lysate is sourced from the HT-1080 cell line, which originates from a fibrosarcoma biopsy taken from a human patient. First isolated and characterized in the early 1970s, this cell line has since been adopted widely in research due to its aggressive growth characteristics and its ability to model fibroblast activity. The lysate is produced by lysing these cells, a process which involves breaking the cell membranes to release their internal contents, including a diverse array of proteins, nucleic acids, lipids, and other small molecules reflective of the cell's metabolic state at the time of lysis. This whole cell lysate provides researchers with a rich source of cellular material for biochemical studies and has been pivotal in research aimed at understanding the mechanisms of cell migration, invasion, and the extracellular matrix composition. In the realm of biological research, HT-1080 lysates are particularly valuable for studying signaling pathways that contribute to cellular motility and the maintenance of the cytoskeleton. They have also been instrumental in the development of assays for examining cell adhesion, a critical factor in cellular communication and tissue cohesion. By providing a detailed molecular snapshot of fibrosarcoma cells, HT-1080 Whole Cell Lysate aids in advancing fundamental research into cellular dynamics and interactions within a highly active cellular environment.

HT-1080 Whole Cell Lysate References:

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