HSV-2 gG Antibody (H1206): sc-69805

HSV-2 gG Antibody (H1206) is a mouse monoclonal IgG1 antibody that detects HSV-2 gG protein of HSV-2 origin by western blotting (WB) and immunofluorescence (IF). Anti-HSV-2 gG antibody (H1206) is available as the non-conjugated format, providing researchers with a reliable tool for studying this important viral protein. Glycoprotein G (gG) plays a crucial role in the pathogenesis of herpes simplex virus type 2 (HSV-2) by facilitating viral entry into host cells and modulating the immune response. HSV-2 gG protein is located on the surface of the virus, where gG interacts with host cell receptors, thereby promoting viral attachment and fusion. This interaction is vital for the establishment of infection and the subsequent spread of the virus within the host. Additionally, gG is involved in evading the host′s immune system, making gG a significant target for therapeutic interventions and vaccine development. The mature gG-2 form, which is heavily O-glycosylated, serves as a type-specific antigen in the serodiagnosis of HSV-2 infection, highlighting gG′s importance in both clinical diagnostics and research applications.

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HSV-2 gG Antibody (H1206) References:

1. Antibody responses to the herpes simplex virus type 2 glycoprotein G in sera of human immunodeficiency virus-infected patients in Slovakia.  |  Bystrická, M., et al. 1998. Acta Virol. 42: 319-24. PMID: 10358733
2. Monoclonal antibodies suitable for type-specific identification of herpes simplex viruses by a rapid culture assay.  |  Bystrická, M., et al. 1999. Acta Virol. 43: 399-402. PMID: 10825932
3. Conservation of type-specific B-cell epitopes of glycoprotein G in clinical herpes simplex virus type 2 isolates.  |  Liljeqvist, JA., et al. 2000. J Clin Microbiol. 38: 4517-22. PMID: 11101589
4. Seroreactive recombinant herpes simplex virus type 2-specific glycoprotein G.  |  Parkes, DL., et al. 1991. J Clin Microbiol. 29: 778-81. PMID: 1653787
5. Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2.  |  Bystrická, M., et al. 1991. Acta Virol. 35: 152-64. PMID: 1681713
6. Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection.  |  Bystrická, M., et al. 1997. Acta Virol. 41: 5-12. PMID: 9199708

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HSV-2 gG Antibody (H1206) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HSV-2 gG Antibody (H1206) Specifications

Alternate Product Name: HSV-2 gG

Product Clone Name: H1206

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: HSV-2 gG

Epitope Species: HSV-2

Product Reactivity/Detection: gG, also designated glycoprotein G,

Species Reactivity/Detection: HSV-2

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for HSV-2 gG Antibody (H1206): N/A