HSV-1 gG Envelope Protein Antibody (7F5) is a mouse monoclonal IgG2a antibody that detects HSV-1 gG Envelope Protein of Herpes Simplex Virus 1 origin by western blotting (WB) and immunofluorescence (IF). HSV-1 gG Envelope Protein (7F5) antibody is available as the non-conjugated anti-HSV-1 gG Envelope Protein antibody. HSV-1 gG Envelope Protein plays a crucial role in viral evasion of host immune response and facilitates viral entry into host cells. HSV-1 gG Envelope Protein interacts with various host cell receptors, enabling virus attachment and fusion with host cell membrane. Through receptor binding, HSV-1 gG Envelope Protein aids in viral entry and modulates immune response, allowing viral establishment and maintenance of latency within sensory ganglia. HSV-1′s ability to remain dormant in nerve cells creates treatment challenges due to potential reactivation and recurrent infections. Understanding HSV-1 gG Envelope Protein function remains essential for developing therapeutic strategies that could disrupt these interactions and lead to more effective HSV infection treatments.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HSV-1 gG Envelope Protein Antibody (7F5) References:
- Herpes simplex virus type 2 (HSV-2) infection in women attending an antenatal clinic in the South Pacific island nation of Vanuatu. | Haddow, LJ., et al. 2007. Sex Transm Dis. 34: 258-61. PMID: 16940899
- The microenvironment of vulvar skin in women with symptomatic and asymptomatic herpes simplex virus type 2 (HSV-2) infection. | Löwhagen, GB., et al. 2006. J Eur Acad Dermatol Venereol. 20: 1086-9. PMID: 16987263
- Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors. | Iqbal, J., et al. 2007. J Chromatogr B Analyt Technol Biomed Life Sci. 846: 281-90. PMID: 17023224
- The HSV-2 protein ICP10PK prevents neuronal apoptosis and loss of function in an in vivo model of neurodegeneration associated with glutamate excitotoxicity. | Golembewski, EK., et al. 2007. Exp Neurol. 203: 381-93. PMID: 17046754
- Association between HSV-2 and HIV-1 viral load in semen, cervico-vaginal secretions and genital ulcers of Thai men and women. | Chu, K., et al. 2006. Int J STD AIDS. 17: 681-6. PMID: 17059638
- HSV infection and immunosuppression. | Sindhi, R. 2006. Liver Transpl. 12: 1906-7. PMID: 17133569
- Sulfasalazine unveils a contact-independent HSV-TK/ganciclovir gene therapy bystander effect in malignant gliomas. | Robe, PA., et al. 2007. Int J Oncol. 30: 283-90. PMID: 17143539
- Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts. | Margolis, TP., et al. 2007. J Virol. 81: 1872-8. PMID: 17151134
- HSV-2- and HIV-1- permissive cell lines co-infected by HSV-2 and HIV-1 co-replicate HSV-2 and HIV-1 without production of HSV-2/HIV-1 pseudotype particles. | Legoff, J., et al. 2007. Virol J. 4: 2. PMID: 17207276