


HoxD8 Antibody (3G8) is a mouse monoclonal IgG2a antibody that detects HoxD8 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). HoxD8, also known as HOX4E, is a 290 amino acid protein that plays a crucial role in the regulation of gene expression during embryonic development, particularly in the formation and positioning of limb buds along the anterior-posterior axis. Anti-HoxD8 antibody (3G8) targets a nuclear protein that functions as a sequence-specific transcription factor, binding to DNA and influencing the transcription of downstream target genes essential for proper morphogenesis. HoxD8 directs the spatial organization of developing structures, and dysregulation has been implicated in various developmental disorders and cancers, including leukemias. HoxD8 (3G8) antibody serves as an invaluable tool for researchers studying the intricate mechanisms of development and differentiation, as well as the pathological conditions associated with aberrant Hox gene expression.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HoxD8 Antibody (3G8) | sc-517116 | 100 µg/ml | $322.00 |