Homovanillic Acid-d3 (CAS 74495-71-9)

Homovanillic Acid-d3 serves as a stable isotope-labeled standard in analytical chemistry for quantifying levels of homovanillic acid, a metabolite of dopamine. Researchers employ this compound in mass spectrometry to improve the accuracy and precision of their measurements due to its deuterium substitution, which provides a distinguishable mass difference from the non-labeled species. It is particularly useful in the field of neurochemistry for studying dopamine metabolism and turnover rates within the central nervous system. Additionally, Homovanillic Acid-d3 is instrumental in environmental studies focusing on the fate and transport of phenolic compounds, as it can act as a tracer that mimics the behavior of similar organic molecules in environmental systems. Its application is also found in the calibration of analytical instruments to ensure the reliability of data, especially in quantitative assays where the detection of small differences in concentration is critical.