Date published: 2025-12-7

1-800-457-3801

SCBT Portrait Logo
Seach Input

Homophthalic acid (CAS 89-51-0)

0.0(0)
Write a reviewAsk a question

Alternate Names:
α-Carboxy-o-toluic acid, 2-Carboxyphenylacetic acid
Application:
Homophthalic acid is a remainder phthalic acid
CAS Number:
89-51-0
Molecular Weight:
180.16
Molecular Formula:
C9H8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Homophthalic acid, also known as 2,5-dihydroxybenzoic acid (DHBA), is a carboxylic acid that stems from benzoic acid. With a molecular formula of C8H6O4, it appears as a white crystalline solid. In scientific research, homophthalic acid is employed for multiple purposes, such as the synthesis of organic compounds, the exploration of enzyme-catalyzed reactions, and the investigation of biological processes like signal transduction. Functionally, homophthalic acid acts as a proton acceptor, actively participating in biochemical reactions. It plays a role in the formation of hydrogen bonds and other interactions with proteins and other molecules. Additionally, homophthalic acid can exhibit catalytic properties, enabling the oxidation of other compounds.


Homophthalic acid (CAS 89-51-0) References

  1. Synthesis of Antitumor Lycorines by Intramolecular Diels-Alder Reaction.  |  Pérez, D., et al. 1996. J Org Chem. 61: 1650-1654. PMID: 11667032
  2. Synthesis and antimicrobial activities of some isocoumarin and dihydroisocoumarin derivatives.  |  Hussain, M., et al. 2003. Nat Prod Res. 17: 207-14. PMID: 12737406
  3. Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives.  |  Sondhi, SM., et al. 2010. Bioorg Med Chem Lett. 20: 2306-10. PMID: 20188544
  4. Two isomorphous transition metal complexes containing a protonated diaminopurine ligand: diaquabis(2,6-diamino-7H-purin-1-ium-κN9)bis(homophthalato-κO)nickel(II) tetrahydrate and the cobalt(II) analogue.  |  Atria, AM., et al. 2011. Acta Crystallogr C. 67: m169-72. PMID: 21540537
  5. Degradation of homophthalic acid byAspergillus niger.  |  Karigar, CS., et al. 1993. Curr Microbiol. 27: 177-80. PMID: 23835751
  6. Synthesis, crystal structures, luminescence and catalytic properties of two d¹⁰ metal coordination polymers constructed from mixed ligands.  |  Wang, XX., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 139: 442-8. PMID: 25576941
  7. Structure and magnetic properties of a copper(II) coordination polymer based on azide, pyridine and homophthalic acid.  |  Ma, J., et al. 2015. Acta Crystallogr C Struct Chem. 71: 969-74. PMID: 26524169
  8. Catabolism of homophthalic acid by a soil bacterium.  |  Karegoudar, TB. and Pujar, BG. 1989. FEMS Microbiol Lett. 49: 305-8. PMID: 2744421
  9. Facile Access to Fe(III)-Complexing Cyclic Hydroxamic Acids in a Three-Component Format.  |  Chupakhin, E., et al. 2019. Molecules. 24: PMID: 30823493
  10. MIL-100(Fe)/g-C3N4 composites with enhanced photocatalytic activity for UO22+ reduction under visible light.  |  Le, Z., et al. 2023. Photochem Photobiol Sci. 22: 59-71. PMID: 36087239
  11. Extending the Scope of the New Variant of the Castagnoli-Cushman Cyclocondensation onto o-Methyl Benzoic Acids Bearing Various Electron-Withdrawing Groups in the α-Position.  |  Guranova, N., et al. 2022. Molecules. 27: PMID: 36364037
  12. [Acylation of homophthalic acid anhydride catalysed by bases. 2. Acylderivates of methylene active dicarbonyl compounds].  |  Schnekenburger, J. and Kaiser, P. 1971. Arch Pharm Ber Dtsch Pharm Ges. 304: 482-92. PMID: 5284068
  13. [Acetylation products of the homophthalic acid anhydride. 8. Acyl derivatives of methylene-active dicarbonyl compounds].  |  Schnekenburger, J. and Kaiser, P. 1971. Arch Pharm Ber Dtsch Pharm Ges. 304: 161-6. PMID: 5291264
  14. Metabolic pathway of homophthalic acid in Pseudomonas alcaligenes.  |  Karigar, CS. and Pujar, BG. 1993. FEMS Microbiol Lett. 110: 59-64. PMID: 8319896

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Homophthalic acid, 25 g

sc-255204
25 g
$53.00