Molecular structure of Hoechst 33342, CAS Number: 23491-52-3
Hoechst 33342 (CAS 23491-52-3)
See product citations (23)
CAS Number:
23491-52-3
Molecular Weight:
561.93
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Hoechst 33342, a long-standing fluorescent dye, has played a role in scientific research for many years. This DNA-binding dye serves as useful for staining and visualizing DNA within cells, providing researchers with a deeper understanding of DNA′s intricate structure and functions. Its versatile applications span various fields, encompassing in vitro studies on gene expression and cellular imaging. Furthermore, Hoechst 33342 finds utility in identifying and quantifying cellular components, including proteins and lipids, offering a comprehensive view of cellular dynamics and composition.
Hoechst 33342 (CAS 23491-52-3) References
- Hoechst 33342 induces apoptosis in HL-60 cells and inhibits topoisomerase I in vivo. | Zhang, X., et al. 1999. Arch Pathol Lab Med. 123: 921-7. PMID: 10506445
- Hoechst 33342-induced apoptosis is associated with intracellular accumulation of E2F-1 protein in BC3H-1 myocytes and HL-60 cells. | Zhang, X. and Kiechle, FL. 2001. Arch Pathol Lab Med. 125: 99-104. PMID: 11151061
- Hoechst 33342 alters luciferase gene expression in transfected BC3H-1 myocytes. | Zhang, X. and Kiechle, FL. 2003. Arch Pathol Lab Med. 127: 1124-32. PMID: 12946233
- Hoechst 33342 is a useful cell tracer for a long-term investigation of articular cartilage repair. | Kawasaki, K., et al. 2004. Arch Histol Cytol. 67: 13-9. PMID: 15125019
- Hoechst 33342 side population identification is a conserved and unified mechanism in urological cancers. | Oates, JE., et al. 2009. Stem Cells Dev. 18: 1515-22. PMID: 19260804
- Hoechst 33342 induces radiosensitization in malignant glioma cells via increase in mitochondrial reactive oxygen species. | Athar, M., et al. 2010. Free Radic Res. 44: 936-49. PMID: 20540663
- Phototoxicity of Hoechst 33342 in time-lapse fluorescence microscopy. | Purschke, M., et al. 2010. Photochem Photobiol Sci. 9: 1634-9. PMID: 20931137
- Assaying Cell Cycle Status Using Flow Cytometry. | Kim, KH. and Sederstrom, JM. 2015. Curr Protoc Mol Biol. 111: 28.6.1-28.6.11. PMID: 26131851
- Hoechst 33342 Is a Hidden 'Janus' amongst Substrates for the Multidrug Efflux Pump LmrP. | Neuberger, A. and van Veen, HW. 2015. PLoS One. 10: e0141991. PMID: 26540112
- Toxicity of Hoechst 33342: implication in side population analysis. | Zheng, J., et al. 2016. Cell Mol Biol (Noisy-le-grand). 62: 27-30. PMID: 27453268
- Discovery of DNA dyes Hoechst 34580 and 33342 as good candidates for inhibiting amyloid beta formation: in silico and in vitro study. | Thai, NQ., et al. 2016. J Comput Aided Mol Des. 30: 639-50. PMID: 27511370
- Analyzing Cell Death by Nuclear Staining with Hoechst 33342. | Crowley, LC., et al. 2016. Cold Spring Harb Protoc. 2016: PMID: 27587774
- Flow Cytometric Detection of G0 in Live Cells by Hoechst 33342 and Pyronin Y Staining. | Eddaoudi, A., et al. 2018. Methods Mol Biol. 1686: 49-57. PMID: 29030811
- Hoechst 33342 as a marker for imaging neurites of Dorsal Root Ganglion in vitro. | Merolli, A. and Bektas, C. 2022. J Anat. 240: 998-1001. PMID: 34811747
- Hoechst 33342 induces apoptosis and alters tata box binding protein/DNA complexes in nuclei from BC3H-1 myocytes. | Zhang, X. and Kiechle, FL. 1998. Biochem Biophys Res Commun. 248: 18-21. PMID: 9675078
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hoechst 33342, 5 ml | sc-495790 | 5 ml | $108.00 |