hnRNP A2/B1 Antibody (DP3B3): sc-32316
- hnRNP A2/B1 Antibody (DP3B3) is a mouse monoclonal IgG2a κ, cited in 35 publications, provided at 200 µg/ml
- raised against bacterially expressed His-hnRNP A2 of human origin
- Anti-hnRNP A2/B1 Antibody (DP3B3) is recommended for detection of hnRNP A2 and hnRNP B1 of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including and bovine, porcine and canine
- Anti-hnRNP A2/B1 Antibody (DP3B3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP is the preferred secondary detection reagent for hnRNP A2/B1 Antibody (DP3B3) for WB applications. This reagent is now offered in a bundle with hnRNP A2/B1 Antibody (DP3B3) (see ordering information below).
hnRNP A2/B1 Antibody (DP3B3) is a mouse monoclonal IgG2a kappa light chain antibody that detects hnRNP A2 and hnRNP B1 proteins of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-hnRNP A2/B1 antibody (DP3B3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Heterogeneous nuclear ribonucleoproteins (hnRNPs) play a crucial role in mRNA metabolism, including transcription, pre-mRNA processing, and mature mRNA transport to the cytoplasm for translation. hnRNP A2 and hnRNP B1 regulate pre-mRNA splicing by influencing splice site selection and modulating splicing factor activity. This regulation is vital for producing functional mRNA, as improper splicing can generate non-functional or deleterious proteins that may contribute to various diseases. The A/B subfamily of hnRNPs, including hnRNP A1, A2/B1, A3, and A0, predominantly localizes in the nucleus, though some members shuttle between the nucleus and cytoplasm, highlighting their dynamic role in gene expression regulation. Understanding hnRNP A2/B1 function and interactions within the spliceosome remains essential for elucidating gene regulation complexities and potential disease implications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
hnRNP A2/B1 Antibody (DP3B3) | sc-32316 | 200 µg/ml | $316.00 | |||
hnRNP A2/B1 Antibody (DP3B3): m-IgG2a BP-HRP Bundle | sc-545916 | 200 µg Ab; 10 µg BP | $354.00 | |||
hnRNP A2/B1 Antibody (DP3B3) AC | sc-32316 AC | 500 µg/ml, 25% agarose | $416.00 | |||
hnRNP A2/B1 Antibody (DP3B3) HRP | sc-32316 HRP | 200 µg/ml | $316.00 | |||
hnRNP A2/B1 Antibody (DP3B3) FITC | sc-32316 FITC | 200 µg/ml | $330.00 | |||
hnRNP A2/B1 Antibody (DP3B3) PE | sc-32316 PE | 200 µg/ml | $343.00 | |||
hnRNP A2/B1 Antibody (DP3B3) Alexa Fluor® 488 | sc-32316 AF488 | 200 µg/ml | $357.00 | |||
hnRNP A2/B1 Antibody (DP3B3) Alexa Fluor® 546 | sc-32316 AF546 | 200 µg/ml | $357.00 | |||
hnRNP A2/B1 Antibody (DP3B3) Alexa Fluor® 594 | sc-32316 AF594 | 200 µg/ml | $357.00 | |||
hnRNP A2/B1 Antibody (DP3B3) Alexa Fluor® 647 | sc-32316 AF647 | 200 µg/ml | $357.00 | |||
hnRNP A2/B1 Antibody (DP3B3) Alexa Fluor® 680 | sc-32316 AF680 | 200 µg/ml | $357.00 | |||
hnRNP A2/B1 Antibody (DP3B3) Alexa Fluor® 790 | sc-32316 AF790 | 200 µg/ml | $357.00 |