HL-60 Cell Lysate for Immunoprecipaitation: sc-24787

The HL-60 (IP) Cell Lysate is derived from the HL-60 cell line, a human promyelocytic cell line used extensively in scientific studies, particularly in the field of hematology and immunology. This cell line was originally established from a patient with acute promyelocytic leukemia and has since played a pivotal role in research due to its ability to differentiate into various types of myeloid cells. The lysate itself is produced by lysing these cells, a process that breaks down the cell membrane, thereby releasing the intracellular contents including proteins, RNA, and DNA. This rich mixture is invaluable for various research applications, including the study of cellular processes, protein interactions, and gene expression. Researchers utilize HL-60 lysates to investigate the molecular underpinnings of cell differentiation and proliferation. Particularly, in proteomics, HL-60 lysates provide a consistent source of human proteins, which are critical for studying protein expression patterns, modifications, and interactions that occur in response to different experimental treatments. This makes HL-60 lysates an essential tool in advancing our understanding of cellular mechanisms at the molecular level, contributing significantly to the field of cellular biology and genetics without delving into direct human impact.