Date published: 2025-12-5

1-800-457-3801

SCBT Portrait Logo
Seach Input

Histamine-α,α,β,β-d4 Dihydrochloride (CAS 344299-48-5)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Peremin-d4; 1H-Imidazole-4-ethanamine-d4 Dihydrochloride; 2-(1H-Imidazol-4-yl)ethanamine-d4 Dihydrochloride
Application:
Histamine-α,α,β,β-d4 Dihydrochloride is a deuterated analog of histamine
CAS Number:
344299-48-5
Molecular Weight:
188.09
Molecular Formula:
C5H7D4Cl2N3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Histamine-α,α,β,β-d4 dihydrochloride is a deuterium-labeled form of histamine, a biogenic amine involved in various physiological responses. In research, this compound is utilized for its stable isotope labeling, which is instrumental in conducting precise quantitative analyses through techniques such as mass spectrometry. Studies employing Histamine-α,α,β,β-d4 dihydrochloride focus on elucidating the metabolism of histamine in biological systems, its role in immunological responses, and its regulatory functions in gastric acid secretion. The compound is also used in the investigation of histamine receptors and their biochemical profiles, providing insights into how histamine modulates various physiological processes. Additionally, it is valuable in tracing the histamine pathways implicated in inflammatory responses and allergic reactions, aiding in the understanding of the underlying mechanisms of these conditions.


Histamine-α,α,β,β-d4 Dihydrochloride (CAS 344299-48-5) References

  1. Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation.  |  Kozak, R., et al. 2020. Front Pharmacol. 11: 1005. PMID: 32733245
  2. Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain.  |  Adams, GL., et al. 2022. J Med Chem. 65: 485-496. PMID: 34931831
  3. Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model of Autism.  |  Eissa, N., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 36015079
  4. Histamine and Serotonin Levels in Bone Marrow Stem Cells Niche as Potential Biomarkers of Systemic Mastocytosis and Myeloproliferative Disorders.  |  Janus, T., et al. 2022. Stem Cell Rev Rep.. PMID: 36577910

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Histamine-α,α,β,β-d4 Dihydrochloride, 1 mg

sc-218580
1 mg
$430.00

Histamine-α,α,β,β-d4 Dihydrochloride, 2.5 mg

sc-218580A
2.5 mg
$750.00

Histamine-α,α,β,β-d4 Dihydrochloride, 5 mg

sc-218580B
5 mg
$1200.00

Histamine-α,α,β,β-d4 Dihydrochloride, 10 mg

sc-218580C
10 mg
$2058.00