HISM Cell Lysate: sc-2229

The HISM Cell Lysate is derived from human intestinal smooth muscle (HISM) cells, which are pivotal for studying the physiology and pathology of the gastrointestinal tract. This lysate is extensively utilized in research focused on understanding the cellular mechanisms governing intestinal motility, smooth muscle contraction, and related signaling pathways. HISM cells are known to express various ion channels, receptors, and contractile proteins, making their lysate an invaluable tool for investigating the biochemical and molecular bases of smooth muscle function. Researchers use the HISM Cell Lysate to examine protein expression profiles, signaling cascades, and interactions among smooth muscle-specific proteins. It is frequently employed in proteomic analyses, Western blotting, and immunoprecipitation studies to identify and quantify proteins involved in muscle contraction and relaxation. Additionally, this lysate is instrumental in studies exploring the effects of various chemical agents on smooth muscle cell signaling and function, aiding in the elucidation of pathways involved in intestinal motility disorders. By providing insights into the regulatory mechanisms of smooth muscle cells, the HISM Cell Lysate significantly contributes to advancing our understanding of gastrointestinal physiology and the complex molecular interactions within intestinal smooth muscle tissue.

HISM Cell Lysate References:

1. Modeling the airway epithelium in allergic asthma: interleukin-13- induced effects in differentiated murine tracheal epithelial cells.  |  Lankford, SM., et al. 2005. In Vitro Cell Dev Biol Anim. 41: 217-24. PMID: 16223336