Hippuric acid (CAS 495-69-2)
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Hippuric acid is a compound of interest in biochemical and environmental research due to its role as a biomarker for exposure to various substances, such as toluene. In the study of xenobiotic metabolism, hippuric acid is examined as a metabolite resulting from the conjugation of benzoic acid with glycine, showcasing a key pathway in the detoxification process in mammals. It is also used in the assessment of renal function, as its clearance from the body can provide information on kidney health. In environmental studies, the presence of hippuric acid in biological samples such as urine is an indicator of environmental or occupational exposure to specific organic compounds. Researchers also utilize hippuric acid in the development of analytical methods for biomonitoring studies. The analysis of hippuric acid concentrations in various biological samples helps in understanding the relationship between exposure levels and potential health effects.
Hippuric acid (CAS 495-69-2) References
- Benzylmercapturic acid is superior to hippuric acid and o-cresol as a urinary marker of occupational exposure to toluene. | Inoue, O., et al. 2004. Toxicol Lett. 147: 177-86. PMID: 14757321
- Hippuric acid as a significant regulator of supersaturation in calcium oxalate lithiasis: the physiological evidence. | Atanassova, SS. and Gutzow, IS. 2013. Biomed Res Int. 2013: 374950. PMID: 24307993
- Hippuric acid in 24 h urine collections as a biomarker of fruits and vegetables intake in kidney stone formers. | Guerra, A., et al. 2014. Int J Food Sci Nutr. 65: 1033-8. PMID: 25198158
- Hippuric Acid levels in paint workers at steel furniture manufacturers in Thailand. | Decharat, S. 2014. Saf Health Work. 5: 227-33. PMID: 25516817
- Validation of a multi-analyte HPLC-DAD method for determination of uric acid, creatinine, homovanillic acid, niacinamide, hippuric acid, indole-3-acetic acid and 2-methylhippuric acid in human urine. | Remane, D., et al. 2015. J Chromatogr B Analyt Technol Biomed Life Sci. 998-999: 40-4. PMID: 26151191
- Urinary Urea, Uric Acid and Hippuric Acid as Potential Biomarkers in Multiple Sclerosis Patients. | Atya, HB., et al. 2018. Indian J Clin Biochem. 33: 163-170. PMID: 29651206
- Preparation of chitosan-modified magnetic Schiff base network composite nanospheres for effective enrichment and detection of hippuric acid and 4-methyl hippuric acid. | Han, J., et al. 2021. J Chromatogr A. 1652: 462373. PMID: 34246963
- Urinary hippuric acid level as a biological indicator of toluene exposure on batik workers. | Oginawati, K., et al. 2021. Heliyon. 7: e07775. PMID: 34430750
- Plasmatic Hippuric Acid as a Hallmark of Frailty in an Italian Cohort: The Mediation Effect of Fruit-Vegetable Intake. | Brunelli, L., et al. 2021. J Gerontol A Biol Sci Med Sci. 76: 2081-2089. PMID: 34436596
- Analytical techniques for monitoring of toluene and xylene exposure biomarkers hippuric acid and methylhippuric acid in human urine samples. | Shan, X., et al. 2021. Bioanalysis. 13: 1569-1584. PMID: 34696600
- Salt formation, hydrogen-bonding patterns and supramolecular architectures of acridine with salicylic and hippuric acid molecules. | Suganya, S., et al. 2021. Acta Crystallogr C Struct Chem. 77: 790-799. PMID: 34864722
- A new method for electrochemical determination of Hippuric acid based on molecularly imprinted copolymer. | Karazan, ZM. and Roushani, M. 2022. Talanta. 246: 123491. PMID: 35462246
- (-)-Epicatechin and its colonic metabolite hippuric acid protect against dexamethasone-induced atrophy in skeletal muscle cells. | Edwards, SJ., et al. 2022. J Nutr Biochem. 110: 109150. PMID: 36049668
- Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy. | Bhandari, D., et al. 2022. Int J Mol Sci. 23: PMID: 36499106
- Hippuric acid and o-cresol in the urine of workers exposed to toluene. | Hasegawa, K., et al. 1983. Int Arch Occup Environ Health. 52: 197-208. PMID: 6629508
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hippuric acid, 5 g | sc-250116 | 5 g | $42.00 | |||
Hippuric acid, 100 g | sc-250116A | 100 g | $47.00 | |||
Hippuric acid, 250 g | sc-250116B | 250 g | $62.00 | |||
Hippuric acid, 1 kg | sc-250116C | 1 kg | $188.00 | |||
Hippuric acid, 5 kg | sc-250116D | 5 kg | $728.00 |