Molecular structure of HIP-B, CAS Number: 227619-65-0
HIP-B (CAS 227619-65-0)
Application:
HIP-B is a potent, non-competitive excitatory amino acid transporter (EAAT) blocker
CAS Number:
227619-65-0
Molecular Weight:
172.14
Molecular Formula:
C6H8N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
HIP-B is a potent, non-competitive excitatory amino acid transporter (EAAT) blocker. HIP-B preferentially inhibits glutamate-induced [3H]D-aspartate release (IC50 = 1.2 µM) rather than [3H]L-glutamate uptake (IC50 = 16.9 µM). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC50 values are 35 and 45 μM respectively).
HIP-B (CAS 227619-65-0) References
1. Conti, P., et al. 1999. J. Med .Chem. 42: 4099-4107.2. Funicello, M., et al. 2004. Mol. Pharmacol. 66:522-529.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HIP-B, 10 mg | sc-203599 | 10 mg | $175.00 | |||
| US: Only available in the US | ||||||