HHV-6 gp90 Antibody (2003): sc-58157

HHV-6 gp90 Antibody (2003) is a mouse monoclonal IgG2 antibody that detects HHV-6 gp90 protein by western blotting (WB), immunoprecipitation (IP), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-HHV-6 gp90 antibody (2003) is available in a non-conjugated form, providing researchers with a versatile tool for studying this important glycoprotein, which is approximately 90 kDa in size. HHV-6 gp90 protein plays a crucial role in the viral life cycle, functioning as a glycoprotein that facilitates viral entry into host cells by interacting with cellular receptors. This interaction enables HHV-6 to establish infection and persist within the host, as HHV-6 can remain latent in various tissues, including monocytes, macrophages, and salivary glands. Understanding HHV-6 gp90′s function is essential for elucidating the pathogenesis of diseases associated with HHV-6, such as febrile illnesses and potential links to demyelinating conditions like multiple sclerosis. The presence of HHV-6 DNA in serum samples of patients with these conditions underscores the importance of studying HHV-6 gp90, as research may provide insights into the virus′s role in disease progression and the development of targeted therapeutic strategies.

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HHV-6 gp90 Antibody (2003) References:

1. The HHV6 paradox: ubiquitous commensal or insidious pathogen? A two-step in situ PCR approach.  |  Blumberg, BM., et al. 2000. J Clin Virol. 16: 159-78. PMID: 10738136
2. Human herpesvirus 6 (HHV6) infection.  |  Abdel-Haq, NM. and Asmar, BI. 2004. Indian J Pediatr. 71: 89-96. PMID: 14979393
3. Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children.  |  Caserta, MT., et al. 2004. J Pediatr. 145: 478-84. PMID: 15480370
4. Lack of association of polyomavirus and herpesvirus types 6 and 7 in human lymphomas.  |  Hernández-Losa, J., et al. 2005. Cancer. 103: 293-8. PMID: 15593086
5. Fatal pulmonary failure attributable to viral pneumonia with human herpes virus 6 (HHV6) in a young immunocompetent woman.  |  Merk, J., et al. 2005. J Intensive Care Med. 20: 302-6. PMID: 16206417
6. [Drug hypersensitivity syndrome associated with a primary HHV6 infection].  |  Debarbieux, S., et al. 2006. Ann Dermatol Venereol. 133: 145-7. PMID: 16508598
7. Human herpesvirus 6 (HHV6) and chronic fatigue syndrome (CFS).  |  Ablashi, DV., et al. 1991. Can Dis Wkly Rep. 17 Suppl 1E: 33-40. PMID: 1669351
8. Three new human herpesviruses (HHV6, 7, and 8).  |  Levy, JA. 1997. Lancet. 349: 558-63. PMID: 9048803
9. The latency rate of human herpesvirus 6 (HHV6) in positive and negative human immunodeficiency virus (HIV) infection of intravenous drug users (IVDU).  |  Jayavasu, C., et al. 1997. Asian Pac J Allergy Immunol. 15: 29-33. PMID: 9251845

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HHV-6 gp90 Antibody (2003) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HHV-6 gp90 Antibody (2003) Specifications

Alternate Product Name: HHV-6 gp90

Product Clone Name: 2003

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₂

Amino Acids:

Epitope Target: HHV-6 gp90

Epitope Species: HHV-6

Product Reactivity/Detection: a 90 KDa glycoprotein

Species Reactivity/Detection: HHV-6

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IHC (P)

Vialing Information: Each vial contains 100 µg IgG₂ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for HHV-6 gp90 Antibody (2003): N/A