Date published: 2026-2-7

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Hexanolamino PAF C-16 (CAS 137566-83-7)

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Application:
Hexanolamino PAF C-16 is a PAF analog with mixed antagonist/agonist properties
CAS Number:
137566-83-7
Molecular Weight:
579.8
Molecular Formula:
C30H62NO7P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexanolamino PAF C-16, a derivative of platelet-activating factor (PAF), has emerged as a significant compound in scientific research for its role in investigating the biological functions and signaling pathways associated with PAF receptors. One area of focus involves elucidating the specific mechanisms of action by which Hexanolamino PAF C-16 interacts with PAF receptors. Research has revealed that Hexanolamino PAF C-16 exhibits high affinity for PAF receptors, particularly subtype 1 (PAF-R1), and can act as either an agonist or antagonist depending on the cellular context and receptor subtype. Upon binding to PAF receptors, Hexanolamino PAF C-16 initiates intracellular signaling cascades that regulate various physiological processes, including inflammation, immune response, and vascular permeability. Additionally, studies have utilized Hexanolamino PAF C-16 as a molecular tool to investigate the role of PAF receptors in diverse biological systems, such as cardiovascular function, respiratory disorders, and neuroinflammation. Furthermore, the development of Hexanolamino PAF C-16 analogs and derivatives has facilitated the exploration of structure-activity relationships and optimization of pharmacological properties, offering insights into potential interventions targeting PAF receptor-mediated pathways. Overall, Hexanolamino PAF C-16 remains a valuable asset in research aimed at unraveling the complexities of PAF signaling and its implications in health and disease.


Hexanolamino PAF C-16 (CAS 137566-83-7) References

  1. Direct Growth Inhibitory Effect of Platelet Activating Factor C-16 and Its Structural Analogs on Mycobacteria.  |  Riaz, MS., et al. 2018. Front Microbiol. 9: 1903. PMID: 30258409
  2. Vasodilator and constrictor actions of platelet-activating factor in the isolated microperfused afferent arteriole of the rabbit kidney. Role of endothelium-derived relaxing factor/nitric oxide and cyclooxygenase products.  |  Juncos, LA., et al. 1993. J Clin Invest. 91: 1374-9. PMID: 8473488

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexanolamino PAF C-16, 1 mg

sc-205342
1 mg
$21.00

Hexanolamino PAF C-16, 10 mg

sc-205342A
10 mg
$170.00