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Hexakis(2,2-difluoroethoxy)phosphazene (CAS 186817-57-2)

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Alternate Names:
Hexakis(1H,1H,2H-perfluoroethoxy)phosphazene
CAS Number:
186817-57-2
Molecular Weight:
621.19
Molecular Formula:
C12H18F12N3O6P3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexakis(2,2-difluoroethoxy)phosphazene is a compound featuring a phosphorus-nitrogen backbone adorned with two fluorine atoms and two ethoxy groups. Its versatility has led to its application as a reagent in organic synthesis, a catalyst in polymerization reactions, and a ligand in coordination chemistry. It has also served as a substrate for enzymatic reactions and a stabilizing agent for proteins. Moreover, researchers have employed Hexakis(2,2-difluoroethoxy)phosphazene in studying the intricacies of protein structure and function.


Hexakis(2,2-difluoroethoxy)phosphazene (CAS 186817-57-2) References

  1. Identification of dimethyldioctadecylammonium ion (m/z 550.6) and related species (m/z 522.6, 494.6) as a source of contamination in mass spectrometry.  |  Manier, ML., et al. 2008. J Am Soc Mass Spectrom. 19: 666-70. PMID: 18328728
  2. In silico modeling and metabolome analysis of long-stored erythrocytes to improve blood storage methods.  |  Nishino, T., et al. 2009. J Biotechnol. 144: 212-23. PMID: 19695295
  3. Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model.  |  Toyohara, T., et al. 2011. Clin Exp Nephrol. 15: 676-687. PMID: 21695416
  4. A yeast metabolite extraction protocol optimised for time-series analyses.  |  Sasidharan, K., et al. 2012. PLoS One. 7: e44283. PMID: 22952947
  5. Dramatic increase in glycerol biosynthesis upon oxidative stress in the anaerobic protozoan parasite Entamoeba histolytica.  |  Husain, A., et al. 2012. PLoS Negl Trop Dis. 6: e1831. PMID: 23029590
  6. Metabolic profiling to identify potential serum biomarkers for gastric ulceration induced by nonsteroid anti-inflammatory drugs.  |  Takeuchi, K., et al. 2013. J Proteome Res. 12: 1399-407. PMID: 23336624
  7. Metabolic Profiling with Gas Chromatography-Mass Spectrometry and Capillary Electrophoresis-Mass Spectrometry Reveals the Carbon-Nitrogen Status of Tobacco Leaves Across Different Planting Areas.  |  Zhao, J., et al. 2016. J Proteome Res. 15: 468-76. PMID: 26784525
  8. Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles.  |  Yamano, E., et al. 2016. Sci Rep. 6: 34990. PMID: 27725700
  9. Comprehensive investigation of tobacco leaves during natural early senescence via multi-platform metabolomics analyses.  |  Li, L., et al. 2016. Sci Rep. 6: 37976. PMID: 27897248
  10. A Transient Rise in Free Mg2+ Ions Released from ATP-Mg Hydrolysis Contributes to Mitotic Chromosome Condensation.  |  Maeshima, K., et al. 2018. Curr Biol. 28: 444-451.e6. PMID: 29358072
  11. Soft Picosecond Infrared Laser Extraction of Highly Charged Proteins and Peptides from Bulk Liquid Water for Mass Spectrometry.  |  Lu, Y., et al. 2018. Anal Chem. 90: 4422-4428. PMID: 29522677
  12. Reprogramming of glutamine metabolism via glutamine synthetase silencing induces cisplatin resistance in A2780 ovarian cancer cells.  |  Guo, J., et al. 2021. BMC Cancer. 21: 174. PMID: 33596851
  13. Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue.  |  Yoshida, Y., et al. 2022. iScience. 25: 104268. PMID: 35521515

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexakis(2,2-difluoroethoxy)phosphazene, 250 mg

sc-263382
250 mg
$400.00

Hexakis(2,2-difluoroethoxy)phosphazene, 1 g

sc-263382A
1 g
$980.00