Date published: 2026-2-10

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Hexafluoroglutaryl chloride (CAS 678-77-3)

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Alternate Names:
Perfluoroglutaryl Chloride; Hexafluoropentane-1,5-dioyl chloride
CAS Number:
678-77-3
Molecular Weight:
276.95
Molecular Formula:
C5Cl2F6O2
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexafluoroglutaryl chloride, a highly reactive compound distinguished by its two acyl chloride groups linked by a hexafluorinated carbon chain, plays a pivotal role in synthetic organic chemistry and materials science research. Its mechanism of action revolves around its ability to act as an acylating agent, making it integral to the synthesis of complex organic molecules, polymers, and fluorinated compounds. Researchers leverage hexafluoroglutaryl chloride′s reactivity towards nucleophiles, such as water, alcohols, and amines, to introduce fluorinated carbonyl groups into target molecules, thereby modifying their chemical properties. This reactivity is also exploited in the development of high-performance materials with enhanced stability, chemical resistance, and unique electronic properties. Hexafluoroglutaryl chloride′s distinctive structure and reactivity profile make it useful in advancing the frontiers of fluorine chemistry and the design of novel fluorinated materials.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexafluoroglutaryl chloride, 1 g

sc-263376
1 g
$38.00

Hexafluoroglutaryl chloride, 5 g

sc-263376A
5 g
$183.00